1. Metabolic Enzyme/Protease Immunology/Inflammation
  2. Cytochrome P450 Aryl Hydrocarbon Receptor
  3. hCYP1B1-IN-1

hCYP1B1-IN-1 (compound B18) 是一种 hCYP1B1 抑制剂 (IC50=3.6 nM),也是芳烃受体的拮抗剂。hCYP1B1-IN-1 具有良好的代谢稳定性和细胞渗透性,并抑制 MCF-7 细胞的迁移。

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hCYP1B1-IN-1 Chemical Structure

hCYP1B1-IN-1 Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

hCYP1B1-IN-1 (compound B18) is a hCYP1B1 inhibitor (IC50=3.6 nM),as well as an antagonist of Aryl Hydrocarbon Receptor. hCYP1B1-IN-1 exhibtis suitable metabolic stability and good cell-permeability. hCYP1B1-IN-1 inhibits migration of MCF-7 cells[1].

IC50 & Target

IC50: 3.6 nM (hCYP1B1)[1]

分子量

370.75

Formula

C18H14ClF3O3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
hCYP1B1-IN-1
目录号:
HY-155061
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