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  4. Hydroxypropyl Cellulose

Hydroxypropyl Cellulose  (Synonyms: 低粘度羟丙基纤维素)

目录号: HY-100557 纯度: ≥97.0%
COA 产品使用指南 技术支持

Hydroxypropyl Cellulose 是一种口服活性纤维素醚和表面活性剂。Hydroxypropyl Cellulose 分为高取代度 HPC (HHPC) 和低取代度 HPC (HHPC)。Hydroxypropyl Cellulose 可降低炎症介质 (IL-6、IL-1β)。Hydroxypropyl Cellulose 可改善结肠炎和肥胖。Hydroxypropyl Cellulose 可用作药用辅料，例如包衣剂、乳化剂、悬浮剂、片剂、增稠剂、增粘剂。

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Hydroxypropyl Cellulose Chemical Structure

Hydroxypropyl Cellulose Chemical Structure

CAS No. : 9004-64-2

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规格 价格 是否有货 数量
5 g ￥100
In-stock
10 g ￥125
In-stock
25 g ￥160
In-stock
50 g ￥200
In-stock
100 g ￥255
In-stock
500 g ￥385
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> 100 g   询价  

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Hydroxypropyl Cellulose 相关抗体

Top Publications Citing Use of Products

查看 Interleukin Related 亚型特异性产品:

查看所有亚型
IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Hydroxypropyl Cellulose is an orally active cellulose ether and surfactant. Hydroxypropyl cellulose is divided into high-substituted HPC (HHPC) and low-substituted HPC (LHPC). Hydroxypropyl Cellulose reduces inflammatory mediators (IL-6, IL-1β). Hydroxypropyl Cellulose improves colitis and obesity. Hydroxypropyl Cellulose can be used as a pharmaceutical excipient, such as coating agent, emulsifier, suspension, tablet, thickener, viscosifier[1][2][3][4].

体外研究
(In Vitro)

Hydroxypropyl methylcellulose (HHPC; 12.5-1600 μg/mL; 24 h) 促进 RAW 264.7 细胞生长并抑制炎症[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Hydroxypropyl Cellulose 相关抗体:
体内研究
(In Vivo)

Hydroxypropyl methylcellulose (150-300 mg/kg；口服；8 天) 可改善 Balb/c 小鼠 DSS 诱发的结肠炎[3]。
Hydroxypropyl methylcellulose (饮食中添加 6%；口服；5 周) 可改善高脂饮食对 DIO 小鼠肠道通透性、胰岛素抵抗、肝脏脂质蓄积、糖皮质激素相关胆汁酸循环、氧化应激和体重增加的影响[4]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Balb/c male mice (DSS-induced colitis model)[3]
Dosage: 150 mg/kg, 300 mg/kg (suspended in water)
Administration: Oral administration, 8 days
Result: Mitigated the pathological damage of colon tissue.
Suppressed spleen edema, preserved thymus index, reduced the serum level of inflammatory mediators (TNF-α, IL-6, IL-1β, and MPO).
Increased the secretion of sIgA in the colon, and restored the balance of the intestinal flora.
CAS 号
性状

固体

颜色

White to off-white

中文名称

低粘度羟丙基纤维素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
溶解性数据
细胞实验： 

H2O 中的溶解度 : 50 mg/mL (超声助溶)

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳，请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度，如有需要，请与 MCE 中国技术支持联系。
纯度 & 产品资料

纯度: ≥97.0%

COA (292 KB)

产品使用指南 (1538 KB)
参考文献

Hydroxypropyl Cellulose 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hydroxypropyl Cellulose9004-64-2低粘度羟丙基纤维素Biochemical Assay ReagentsInterleukin RelatedILpharmaceutical excipientpharmaceutical auxiliariepharmaceutical ingredientsinactive ingredientsstabilitysolubilityprocessabilityabsorptiondistributionmetabolismand elimination (ADME)Inhibitorinhibitorinhibit

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目录号：
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