2. Cell Cycle/DNA Damage Neuronal Signaling
  3. IRE1 Amyloid-β
  4. IXA62

IXA62 是具有口服活性的、选择性的 IRE1/XBP1s 激动剂 (EC50 = 0.31 μM)，可减少 Aβ 分泌。IXA62 可增强大鼠胰岛素瘤细胞葡萄糖刺激下的胰岛素分泌。

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IXA62 Chemical Structure

IXA62 Chemical Structure

CAS No. : 956783-34-9

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规格 价格 是否有货 数量
5 mg ￥2900
3 - 4 周
10 mg ￥3950
3 - 4 周
25 mg 现货 3 - 4 周
50 mg 现货 3 - 4 周
100 mg   询价  
200 mg   询价  

* Please select Quantity before adding items.

Customer Review

IXA62 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

IXA62 is an orally active and selective IRE1/XBP1s activator (EC50 = 0.31 μM) that reduces Aβ secretion. IXA62 enhances glucose-stimulated insulin secretion from rat insulinoma cells[1].

体外研究
(In Vitro)

IXA62 是一种选择性 IRE1/XBP1s 激活剂，能够减少 CHO7PA2 细胞中 Aβ 的分泌，并增强大鼠胰岛瘤细胞的葡萄糖刺激胰岛素分泌，在这些实验中表现出类似 IXA4 的作用。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IXA62 相关抗体:
体内研究
(In Vivo)

IXA62 (orally, or i.p, 50 mg/kg) 在小鼠肝脏中稳健且选择性地激活 IRE1/XBP1s 信号通路[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

401.46

Formula

C24H23N3O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

IXA62 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IXA62956783-34-9IXA 62IXA-62IRE1Amyloid-βInositol requiring enzyme 1β-amyloid peptideAβAbetaInhibitorinhibitorinhibit

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目录号：
HY-176040
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