2. GPCR/G Protein MAPK/ERK Pathway
  3. Ras
  4. KRAS G12D-IN-29

KRAS G12D inhibitor 29 (Compound Formula (I)) 是一种具有口服活性且选择性的 KRASG12D 抑制剂。KRAS G12D inhibitor 29 能阻断由 KRAS G12D 介导的下游信号通路，从而抑制肿瘤细胞的增殖。KRAS G12D inhibitor 29 有望用于与 KRAS G12D 突变相关的癌症的研究，如胰腺癌、肺癌、结肠癌。

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KRAS G12D-IN-29 Chemical Structure

KRAS G12D-IN-29 Chemical Structure

CAS No. : 3018057-89-8

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KRAS G12D-IN-29 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

KRAS G12D inhibitor 29 (Compound Formula (I)) is an orally active and selective KRASG12D mutant inhibitor. KRAS G12D inhibitor 29 blocks downstream signaling pathways mediated by KRASG12D, suppressing tumor cell proliferation. KRAS G12D inhibitor 29 is promising for research of KRASG12D mutation-related cancers (such as pancreatic cancer, lung cancer, colorectal cancer)[1].

IC50 & Target

KRas G12D

 

分子量

649.63

Formula

C31H33F6N7O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

KRAS G12D-IN-29 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KRAS G12D-IN-293018057-89-8Rasorally activeKRASG12DcancersInhibitorinhibitorinhibit

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产品名称：
KRAS G12D-IN-29
目录号：
HY-176523
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