1. Academic Validation
  2. The Use of Antimalarial Drugs against Viral Infection

The Use of Antimalarial Drugs against Viral Infection

  • Microorganisms. 2020 Jan 8;8(1):85. doi: 10.3390/microorganisms8010085.
Sarah D'Alessandro 1 Diletta Scaccabarozzi 2 Lucia Signorini 1 Federica Perego 1 Denise P Ilboudo 3 Pasquale Ferrante 1 Serena Delbue 1
Affiliations

Affiliations

  • 1 Department of Biomedical, Surgical and Dental Sciences, University of Milano, 20133 Milan, Italy.
  • 2 Department of Pharmacological and Biomolecular Sciences, University of Milano, 20133 Milan, Italy.
  • 3 Département des Sciences de la Vie, University of Fada N'Gourma (UFDG), Fada N'Gourma BP 54, Burkina Faso.
Abstract

In recent decades, drugs used to treat malaria Infection have been shown to be beneficial for many Other Diseases, including viral infections. In particular, they have received special attention due to the lack of effective Antiviral drugs against new emerging viruses (i.e., HIV, dengue virus, chikungunya virus, Ebola virus, etc.) or against classic infections due to drug-resistant viral strains (i.e., human cytomegalovirus). Here, we reviewed the in vitro/in vivo and clinical studies conducted to evaluate the Antiviral activities of four classes of antimalarial drugs: Artemisinin derivatives, aryl-aminoalcohols, aminoquinolines, and antimicrobial drugs.

Keywords

antimalarial drugs; emerging infections; viruses.

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