2. Cell Cycle/DNA Damage Cytoskeleton
  3. Mps1
  4. Mps1-IN-6

Mps1-IN-6 是一种有效的 Mps1 抑制剂，IC50 值为 2.596 nM。Mps1-IN-6 显示出抗增殖活性。Mps1-IN-6 具有抗癌活性。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Mps1-IN-6 Chemical Structure

Mps1-IN-6 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Mps1-IN-6 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Mps1-IN-6 is a potent Mps1 inhibitor with an IC50 value of 2.596 nM. Mps1-IN-6 shows antiproliferative activity. Mps1-IN-6 shows antitumor activity[1].

IC50 & Target

IC50: 2.596 nM (Mps1)[1]
体外研究
(In Vitro)

Mps1-IN-6 (compound 31) (0-10 µM; 72 h) 显示抗增殖活性，对于 MDA-MB-468，MCF-7, REB，MV4-11，HT-29 细胞的 IC50 值分别为 0.221, >10, >10, 0.823, >10 µM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Mps1-IN-6 相关抗体:

Cell Proliferation Assay[1]

Cell Line: MDA-MB-468, MCF-7, REB, MV4-11, HT-29 cells
Concentration: 0-10 µM
Incubation Time: 72 h
Result: Showed antiproliferative activity with IC50s of 0.221, >10, >10, 0.823, >10 µM for MDA-MB-468, MCF-7, REB, MV4-11, HT-29 cells, respectively.
体内研究
(In Vivo)

Mps1-IN-6 (30, 60 mg/kg; i.v.; once daily for 21 days) 在小鼠体内显示出抗肿瘤活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Six to eight week-old female BALB/c nude mice (MDA-MB-468 mouse xenograft model)[1]
Dosage: 30, 60 mg/kg
Administration: I.v.; once daily for 21 days
Result: Inhibited the tumor growth with TGI values of 21%, 34% for 30, 60 mg/kg, respectively.
分子量

633.74

Formula

C35H39N9O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Mps1-IN-6 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mps1-IN-6Mps1Monopolar spindle 1antiproliferativeantitumorMDA-MB-468 cellsInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Mps1-IN-6
目录号：
HY-149959
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z