2. Others Metabolic Enzyme/Protease
  3. Reference Standards Drug Metabolite
  4. N-Desethyl Sunitinib hydrochloride (Standard)

N-Desethyl Sunitinib hydrochloride (Standard)  (Synonyms: SU-12662 hydrochloride (Standard))

目录号: HY-138813R 纯度: ≥98%
产品使用指南 技术支持

N-Desethyl Sunitinib (hydrochloride) (Standard)是 N-Desethyl Sunitinib (hydrochloride) 的分析标准品。本产品用于研究及分析应用。N-Desethyl Sunitinib (SU-12662) (hydrochloride) 是 Sunitinib 的代谢物。Sunitinib 是有效的，ATP 竞争的 VEGFR，PDGFRβ 和 KIT 抑制剂，能够抑制 VEGFR -1，VEG

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N-Desethyl Sunitinib hydrochloride (Standard) Chemical Structure

N-Desethyl Sunitinib hydrochloride (Standard) Chemical Structure

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规格 是否有货
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生物活性

Glycochenodeoxycholic acid sodium salt (Standard) is the analytical standard of Glycochenodeoxycholic acid sodium salt. This product is intended for research and analytical applications. Glycochenodeoxycholic acid sodium salt (Sodium glycochenodeoxycholate) is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid sodium salt inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver cells, leading to the Apoptosis of human hepatocyte cells. Glycochenodeoxycholic acid sodium salt induces stemness and chemoresistance via activating STAT3 signaling pathway in hepatocellular carcinoma cells (HCC). Glycochenodeoxycholic acid sodium salt is promising for research in the field of cholestasis desease, hepatocellular carcinoma and primary sclerosing cholangitis (PSC).

分子量

406.88

Formula

C20H24ClFN4O2
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

N-Desethyl Sunitinib hydrochloride (Standard) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Desethyl Sunitinib hydrochloride (Standard)SU-12662 hydrochloride (Standard)Reference StandardsDrug MetabolitehydrochloridemetabolitesunitinibpotentATP-competitiveInhibitorinhibitorinhibit

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