1. Apoptosis
  2. Bcl-2 Family Apoptosis
  3. Oblimersen sodium

Oblimersen sodium 是一种针对 BCL-2 RNA的抑制剂。Oblimersen sodium 与 BCL-2 mRNA 序列的前六个密码子特异性结合,导致BCL-2 mRNA 降解,并通过下调 BCL-2 的表达诱导细胞凋亡。Oblimersen sodium 可用于癌症研究。

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DNA, d(P-thio)(T-C-T-C-C-C-A-G-C-G-T-G-C-G-C-C-A-T), sodium salt

Oblimersen sodium Chemical Structure

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查看 Bcl-2 Family 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Oblimersen sodium is a BCL-2 inhibitor targeting BCL-2 RNA. Oblimersen sodium specifically binds to the first six codons of the bcl-2 mRNA sequence, resulting in degradation of bcl-2 mRNA and induces apoptosis by down-regulating expression of Bcl-2. Oblimersen sodium can be used for cancer research[1][2][3].

分子量

6058.28

Formula

C172H204N62Na17O91P17S17

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Oblimersen sodium 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Oblimersen sodium
目录号:
HY-118874A
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