2. GPCR/G Protein Neuronal Signaling Membrane Transporter/Ion Channel
  3. mAChR Potassium Channel
  4. Oxybutynin chloride (Standard)

Oxybutynin chloride (Standard)  (Synonyms: 盐酸奥昔布宁 (标准品))

目录号: HY-B0267AR 纯度: ≥98%
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Oxybutynin (chloride) (Standard) 是 Oxybutynin (chloride) 的分析标准品。本产品用于研究及分析应用。 Oxybutynin chloride 是一种口服有效的、竞争性的 mAChR 拮抗剂，其在小鼠膀胱和大脑皮层中特异性 [3H]NMS 结合的 Ki 值分别为 14.3 和 5.55 nM。Oxybutynin chloride 能够以不依赖其抗胆碱能效应的方式抑制血管 Kv 通道，IC50 值为 11.51 μM。Oxybutynin chloride 能有效减少膀胱和尿路的肌肉痉挛，可用于膀胱过度活动症的研究。

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Oxybutynin chloride (Standard) Chemical Structure

Oxybutynin chloride (Standard) Chemical Structure

CAS No. : 1508-65-2

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生物活性

Oxybutynin (chloride) (Standard) is the analytical standard of Oxybutynin (chloride). This product is intended for research and analytical applications. Oxybutynin chloride is an oral active and competitive mAChR antagonist with Kis of 14.3 and 5.55 nM for specific [3H]NMS binding in the mouse bladder and cerebral cortex, respectively. Oxybutynin chloride inhibits vascular Kv channels in a manner independent of anticholinergic effect, with an IC50 value of 11.51 μM. Oxybutynin chloride reduces muscle spasm in the bladder and urinary tract, can be used in study of overactive bladder syndrome (OAB). Oxybutynin (chloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

分子量

393.95

Formula

C22H32ClNO3
CAS 号
中文名称

盐酸奥昔布宁 (标准品)
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
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Oxybutynin chloride (Standard) 相关分类

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Keywords:

Oxybutynin chloride (Standard)1508-65-2盐酸奥昔布宁 (标准品)mAChRPotassium ChannelMuscarinic acetylcholine receptorKcsAInhibitorinhibitorinhibit

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