2. Cytoskeleton Membrane Transporter/Ion Channel
  3. Dynamin ATP Synthase
  4. P259

P259 是一种 Drp1-Mff 抑制剂。P259 通过特异性抑制 Drp1-Mff 相互作用来区分生理性裂变和病理性裂变。P259 会延长细胞线粒体，并破坏线粒体的功能和运动能力。P259 降低脑内 ATP 水平并改变线粒体结构，导致野生型小鼠出现行为缺陷，并缩短 Huntington's disease (HD) 模型小鼠的寿命。

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Custom Peptide Synthesis

P259 Chemical Structure

P259 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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Customer Review

P259 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

P259 is a Drp1-Mff inhibitor. P259 distinguishes physiological from pathological fission by specifically inhibiting Drp1-Mff interaction. P259 elongates cell mitochondria and disrupts mitochondrial function and motility. P259 reduces ATP levels and alters mitochondrial structure in the brain, resulting in behavioral deficits in wild-type mice and a short lifespan in Huntington's disease (HD) mice model[1].

分子量

1122.40

Formula

C54H95N11O14
Sequence

Ile-Ile-Gln-Leu-Pro-Glu-Ile-Val-Val-Val
Sequence Shortening

IIQLPEIVVV
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

P259 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

P259P 259P-259DynaminATP SynthaseDrp1-MffInhibitorMitochondrial functionATPHuntington's diseaseHDinhibitorinhibit

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目录号：
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