2. Others Cell Cycle/DNA Damage Epigenetics Autophagy Anti-infection Apoptosis
  3. Reference Standards HDAC Autophagy HIV Apoptosis
  4. Panobinostat (Standard)

Panobinostat (Standard)  (Synonyms: LBH589 (Standard); NVP-LBH589 (Standard))

目录号: HY-10224R 纯度: ≥98%
产品使用指南 技术支持

Panobinostat (Standard) (LBH589 (Standard)) 是 Panobinostat (HY-10224) 的分析标准品。本产品用于研究及分析应用。Panobinostat 是一种有效的口服非选择性 HDAC 抑制剂，具有抗肿瘤活性。Panobinostat 可诱导 HIV-1 virus 的产生，即使在较低的浓度范围 8-31 nM，也可刺激 HIV-1 在潜伏感染细胞中的表达。Panobinostat 诱导细胞凋亡 (apoptosis) 和自噬 (autophagy)。Panobinostat 可用于难治性或复发性多发性骨髓瘤的研究。

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Panobinostat (Standard) Chemical Structure

Panobinostat (Standard) Chemical Structure

CAS No. : 404950-80-7

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规格 价格 是否有货 数量
5 mg ￥1218
In-stock
10 mg ￥1950
In-stock
25 mg ￥3510
In-stock
50 mg ￥5620
In-stock
100 mg ￥9000
In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

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生物活性

Panobinostat (Standard) (LBH589 (Standard)) is the analytical standard of Panobinostat (HY-10224). This product is intended for research and analytical applications. Panobinostat is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities. Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells. Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma.

分子量

349.43

Formula

C21H23N3O2
CAS 号
性状

固体

颜色

Off-white to light yellow

中文名称

帕比司他标准品
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Panobinostat (Standard) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Panobinostat (Standard)404950-80-7LBH589 (Standard)NVP-LBH589 (Standard)帕比司他标准品Reference StandardsHDACAutophagyHIVApoptosisHistone deacetylasesHuman immunodeficiency virusInhibitorinhibitorinhibit

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