2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. Poneratoxin

Poneratoxin 是一种肽毒素，可调节哺乳动物的钠电流，并引起持久疼痛。

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Custom Peptide Synthesis

Poneratoxin Chemical Structure

Poneratoxin Chemical Structure

CAS No. : 137084-94-7

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Poneratoxin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Poneratoxin is a peptide toxin, which regulates the sodium currents in mammalian, and causes long-lasting pain[1].

体内研究
(In Vivo)

Poneratoxin 在 C57BL/6 J 小鼠模型中引起立即和持久的伤害行为 (20 至 600 pmol，足底注射，单剂量)，并在苍蝇模型中导致麻痹，PD50 (1 h) 为 74.3 nmol /g (0-100 nmol/g，腹腔注射，单剂量)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: C57BL/6 J mice model[1]
Dosage: 20 to 600 pmol
Administration: intraplantar injection, single dose
Result: Caused spontaneous nocifensive behaviours.
Animal Model: blowflies model[1]
Dosage: 0-100 nmol/g
Administration: Ip, single dose
Result: Caused paralysis.
分子量

2756.35

Formula

C129H215N33O31S
CAS 号
Unlabeled CAS

Sequence

Phe-Leu-Pro-Leu-Leu-Ile-Leu-Gly-Ser-Leu-Leu-Met-Thr-Pro-Pro-Val-Ile-Gln-Ala-Ile-His-Asp-Ala-Gln-Arg-NH2
Sequence Shortening

FLPLLILGSLLMTPPVIQAIHDAQR-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Poneratoxin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Poneratoxin137084-94-7Sodium ChannelNa channelsNa+ channelsParaponera clavataC57BL/6?J miceInhibitorinhibitorinhibit

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产品名称：
Poneratoxin
目录号：
HY-P10234
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