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  4. RCD405

RCD405 是一种支气管扩张剂。RCD405 通过直接作用于人体气道平滑肌 (hASM) 发挥松弛作用，对组胺引起的收缩的 EC50 值为 12 μM，对卡巴胆碱引起的收缩的 EC50 值为 45.71 μM。RCD405 可抑制胆碱能和组胺能张力，并减少电刺激 (EFS) 引起的收缩。RCD405 有望用于哮喘和慢性阻塞性肺疾病 (COPD) 的研究。

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RCD405 Chemical Structure

RCD405 Chemical Structure

CAS No. : 2408134-22-3

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RCD405 相关抗体

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  • 生物活性

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生物活性

RCD405 is a bronchodilator. RCD405 exerts relaxant effects by acting directly on human airway smooth muscle (hASM) with an EC50 value of 12 μM for histamine-induced contractions and 45.71 μM for carbachol-induced contractions. RCD405 inhibits cholinergic and histaminergic tone and reduces electrically stimulated (EFS)-induced contractions. RCD405 is promising for research of asthma and chronic obstructive pulmonary disease (COPD)[1].

分子量

453.26

Formula

C17H13Cl2F3N2O3S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

RCD405 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RCD4052408134-22-3RCD 405RCD-405OthersBronchodilatorhASMasthmaCOPDInhibitorinhibitorinhibit

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