B3GNT6 蛋白, Human (sf9, His)

B3GNT6 Protein, a vital beta-1,3-N-acetylglucosaminyltransferase, is crucial for synthesizing the core 3 structure of O-glycans, essential in mucin-type glycoprotein biosynthesis. With a key role in digestive organs, B3GNT6 significantly contributes to glycoconjugate structural diversity and functional properties. Its involvement in core 3 O-glycan synthesis is vital for mucin formation, impacting cell adhesion and mucosal protection processes. Understanding B3GNT6's role enhances glycosylation pathway comprehension, with potential applications in digestive organ physiology and glycan-related therapeutic targets. Further investigation promises insights into mucin-type glycoprotein biosynthesis in health and disease. B3GNT6 Protein, Human (sf9, His) is the recombinant human-derived B3GNT6 protein, expressed by Sf9 insect cells, with N-His labeled tag. The total length of B3GNT6 Protein, Human (sf9, His) is 341 a.a., with molecular weight of ~47 kDa.

B3GNT6 蛋白充当重要的 β-1,3-N-乙酰氨基葡萄糖转移酶，专门负责 O-聚糖核心 3 结构的合成，该结构是粘蛋白型糖蛋白生物合成的重要前体。B3GNT6 在粘蛋白型 O-聚糖（尤其是消化器官中）的合成中发挥着关键作用，对糖复合物的结构多样性和功能特性做出了重大贡献。该酶参与核心 3 O-聚糖合成对于粘蛋白的正常形成和功能至关重要，影响与细胞粘附和粘膜保护相关的过程。了解 B3GNT6 的具体作用可以增强我们对糖基化途径的理解，为阐明消化器官生理学提供潜在的应用，并有助于探索聚糖相关的治疗靶点。对 B3GNT6 功能的进一步研究有望增进我们对粘蛋白型糖蛋白生物合成及其对健康和疾病的影响的了解。

Human

Sf9 insect cells

N-His

Q6ZMB0 (Q44-S384)

192134  [NCBI]

Approximately 47 kDa

Greater than 90% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.