1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Chemokine & Receptors
  4. CXC Chemokines
  5. BCA-1/CXCL13
  6. BCA-1/CXCL13 蛋白, Human (His)

BCA-1/CXCL13 蛋白, Human (His)

目录号: HY-P704362
产品使用指南 技术支持

BCA-1/CXCL13 蛋白选择性吸引 B 淋巴细胞,而不影响 T 淋巴细胞、单核细胞或中性粒细胞。与其他趋化因子不同,它不会诱导 B 淋巴细胞释放钙。BCA-1/CXCL13 蛋白, Human (His) 是重组的 BCA-1/CXCL13 蛋白,由 E. coli 表达,带有 N-His 标签。

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描述

The BCA-1/CXCL13 protein selectively attracts B lymphocytes without affecting T lymphocytes, monocytes, or neutrophils. Unlike other chemokines, it does not induce calcium release from B lymphocytes. BCA-1/CXCL13 Protein, Human (His) is the recombinant human-derived BCA-1/CXCL13 protein, expressed by E. coli, with N-His labeled tag.

研究背景

BCA-1/CXCL13 蛋白充当 B 淋巴细胞的选择性趋化因子,其作用与 T 淋巴细胞、单核细胞和中性粒细胞不同。与其他趋化因子不同,它不会诱导 B 淋巴细胞释放钙。其与 BLR1/CXCR5 的结合证明了其对 B 淋巴细胞的特异性,强调了其在协调 B 细胞迁移中的作用。这种趋化功能和受体结合的选择性使 BCA-1/CXCL13 成为免疫系统中的关键调节剂,有助于细胞微环境中 B 淋巴细胞的精确招募和激活。

种属

Human

表达系统

E. coli

标签

N-His

蛋白编号

O43927-1 (V23-P109)

基因 ID

10563

蛋白结构
N-term
His
CXL13 (V23-P109)
Accession # O43927-1
C-term
蛋白长度

Full Length of Isoform-1 Mature Protein

同用名
BCA-1/CXCL13; C-X-C motif chemokine 13; BCA1; BLC; SCYB13
预测分子量
12.2 kDa
分子量

Approximately 12-15 kDa,based on SDS-PAGE under reducing conditions.

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

BCA-1/CXCL13 Protein, Human (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
BCA-1/CXCL13 Protein, Human (His)
目录号:
HY-P704362
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