FSH beta 蛋白, Human (HEK293, His)

The FSH beta protein and the alpha chain CGA form follicle-stimulating hormone, which gives the hormone heterodimer biological specificity. It binds to FSHR on target cells and initiates downstream signaling, which is critical for follicle development and spermatogenesis. FSH beta Protein, Human (HEK293, His) is the recombinant human-derived FSH beta protein, expressed by HEK293 , with C-6*His labeled tag. The total length of FSH beta Protein, Human (HEK293, His) is 111 a.a., with molecular weight of ~21.0 kDa.

FSH β 蛋白与 α 链 CGA 结合形成促卵泡激素（卵泡刺激激素），赋予激素异二聚体其生物特异性。该蛋白与 FSHR（靶细胞上的 G 蛋白偶联受体）结合，启动下游信号传导通路。促卵泡素在生殖器官的卵泡发育和精子发生中起着至关重要的作用。活性促卵泡素的结构为异二聚体，由与其他激素共享的 α 链/CGA 和独特的 β 链/FSHB 组成。通过与 FSHR 的相互作用，FSH β 蛋白有助于生殖过程的调节，突显其在生育力和生殖健康的复杂协调中的重要性。

Human

HEK293

C-6*His

P01225 (N19-E129)

2488  [NCBI]

NSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVYKDPARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVRGLGPSYCSFGEMKE

Approximately 21.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.