Neurotrophin-3 蛋白, Human (HEK293)

Neurotrophin-3 (NT-3) is crucial for promoting the survival of sensory neurons, specifically those linked to visceral and proprioceptive functions. Its role highlights NT-3's significance in maintaining and supporting the functionality of these specialized sensory cells, emphasizing its potential as a key regulator in the complex network governing essential physiological sensory processes. Neurotrophin-3 Protein, Human (HEK293) is the recombinant human-derived Neurotrophin-3 protein, expressed by HEK293 , with tag free.

Neurotropin-3 (NT-3) 是促进感觉神经元存活的关键因素，特别是那些与内脏和本体感觉功能相关的神经元。NT-3 在支持这些特殊感觉细胞活力方面的作用强调了 NT-3 在协调复杂机制方面的重要性，这些机制有助于内脏和本体感觉神经元群体的维持和功能。NT-3 在促进神经元存活方面的具体作用揭示了其作为复杂网络中关键调节因子的潜力，该网络控制着正常生理功能所必需的感觉过程。

Measured in a cell proliferation assay using BaF3 mouse pro-B cells transfected with TrkB. The ED₅₀ for this effect is 36.23 ng/mL, corresponding to a specific activity is 2.760×10⁴ units/mg.

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  Measured in a cell proliferation assay using BaF3 mouse pro-B cells transfected with TrkB. The ED₅₀ for this effect is 36.23 ng/mL, corresponding to a specific activity is 2.760×10⁴ units/mg.

Human

HEK293

Tag Free

P20783 (Y139-T257)

4908

Full Length of Mature Protein

YAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGRT

Approximately 14 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

<0.1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in PBS. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.