PRPS2 蛋白, Human (HEK293, His)

The PRPS2 protein plays a key role in catalyzing the synthesis of phosphoribosyl pyrophosphate (PRPP), a key intermediate in nucleotide synthesis. By promoting the conversion of ribose 5-phosphate and ATP to PRPP, PRPS2 contributes to the availability of PRPP in various cellular processes, including de novo biosynthesis of purine and pyrimidine nucleotides. PRPS2 Protein, Human (HEK293, His) is the recombinant human-derived PRPS2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PRPS2 Protein, Human (HEK293, His) is 317 a.a., with molecular weight of ~37.0 kDa.

磷酸核糖焦磷酸合成酶 2 (PRPS2) 是一种对核苷酸生物合成至关重要的酶，因为它催化磷酸核糖焦磷酸 (PRPP) 的合成。PRPP 是嘌呤和嘧啶核苷酸从头生物合成的关键前体，对于 DNA 和 RNA 合成至关重要。PRPS2 的酶活性涉及焦磷酸从 ATP 转移到核糖 5-磷酸，形成 PRPP。该反应代表了嘌呤和嘧啶回收途径中的关键步骤，为细胞核苷酸池提供了必要的构建模块。PRPS2 在合成 PRPP 中的作用强调了其在支持基本细胞过程（包括遗传物质的维持和细胞增殖）中的重要性。参考资料：所提供的信息基于截至 2022 年 1 月的一般知识，未引用具体参考资料。

Human

HEK293

C-6*His

P11908 (P2-L318)

5634  [NCBI]

PNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL

Approximately 37.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.