SPG21 蛋白, Mouse (sf9, His)

The SPG21 protein acts as a negative regulator in CD4-dependent T cell activation, suggesting a potential role in the regulation of immune responses. By interacting directly with CD4, it affects key components of the T cell activation pathway. SPG21 Protein, Mouse (sf9, His) is the recombinant mouse-derived SPG21 protein, expressed by Sf9 insect cells , with N-His labeled tag.

SPG21 蛋白似乎在 CD4 依赖性 T 细胞激活中充当负调节因子，表明其在调节免疫反应中具有潜在作用。这种调节功能涉及与 CD4 的直接相互作用，强调其对 T 细胞激活途径关键组成部分的影响。此外，SPG21 蛋白与 ALDH16A1 相互作用，表明它参与了可能超出 T 细胞调节范围的多种分子相互作用。进一步探索 SPG21 在 CD4 依赖性 T 细胞激活背景下的具体机制和下游效应，可以为了解其在免疫调节和免疫系统以外的细胞过程中的作用提供有价值的见解。

Mouse

Sf9 insect cells

N-6*His

Q9CQC8-1 (M1-P308)

27965  [NCBI]

Full Length of Isoform-1

Approximately 35 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

溶液

Supplied as a 0.22 μm filtered solution in 50 mM Tris-HCL, 150 mM NaCl, pH 8.0, 50% Glycerol.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.