2. Gene
  3. Spg21 - SPG21, maspardin Gene

Spg21 - SPG21, maspardin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: MAST; ACP33; GL010; BM-019; D9Wsu18e

基因 ID: 27965 | 基因类型: protein coding

关于 Spg21

功能概要

Predicted to enable CD4 receptor binding activity. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be active in cytosol and trans-Golgi network transport vesicle. Is expressed in extraembryonic component; head mesenchyme; tongue; and vertebral axis musculature. Used to study Mast syndrome. Human ortholog(s) of this gene implicated in Mast syndrome and hereditary spastic paraplegia. Orthologous to human SPG21 (SPG21 abhydrolase domain containing, maspardin). [provided by Alliance of Genome Resources, Apr 2022]

Spg21 基因产物(9)

mRNA Protein Name
NM_001357813.2 NP_001344742.1 maspardin isoform 1
NM_001413545.1 NP_001400474.1 maspardin isoform 2
NM_001413546.1 NP_001400475.1 maspardin isoform 3
NM_001413547.1 NP_001400476.1 maspardin isoform 4
NM_001413548.1 NP_001400477.1 maspardin isoform 5
NM_001413549.1 NP_001400478.1 maspardin isoform 5
NM_001413550.1 NP_001400479.1 maspardin isoform 6
NM_001413551.1 NP_001400480.1 maspardin isoform 7
NM_138584.3 NP_613050.1 maspardin isoform 1
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell growth IMP
IMP: 通过突变表型推断
26978163 MGI
acts upstream of or within collateral sprouting IMP
IMP: 通过突变表型推断
20661613 MGI
acts upstream of or within epidermal growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
26978163 MGI
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
26978163 MGI
acts upstream of or within limb development IMP
IMP: 通过突变表型推断
20661613 MGI
acts upstream of or within locomotory behavior IMP
IMP: 通过突变表型推断
26978163 MGI
acts upstream of or within neuromuscular process IMP
IMP: 通过突变表型推断
26978163 MGI
acts upstream of or within neuron maturation IMP
IMP: 通过突变表型推断
26978163 MGI
acts upstream of or within response to epidermal growth factor IMP
IMP: 通过突变表型推断
26978163 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

maspardin

acid cluster protein 33

spastic paraplegia 21 autosomal recessive Mast syndrome protein homolog

spastic paraplegia 21 homolog

重组 Spg21 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77213 SPG21 Protein, Mouse (sf9, His) Q9CQC8-1 (M1-P308) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13662 SPG21 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20496 Spg21 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27004 Spg21 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Spg21 NCBI NCBI:51324
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