Syndecan-4 蛋白, Human

Studies have proven that Syndecan-4 protein is a cell surface proteoglycan that cooperates with SDCBP and PDCD6IP to play a key role in regulating exosome biogenesis. Syndecan-4 functions as a homodimer and interacts with various intracellular partners through its cytoplasmic domain. Syndecan-4 Protein, Human is the recombinant human-derived Syndecan-4 protein, expressed by E. coli , with tag free.

Syndecan-4 是一种细胞表面蛋白聚糖，与 SDCBP 和 PDCD6IP 合作，成为外泌体生物发生的关键调节因子。它形成同二聚体并与各种蛋白质相互作用，包括通过其胞质结构域的 GIPC 和 NUDT16L1。Syndecan-4 进一步与 CDCP1 和 SDCBP 相互作用，强调其参与多种细胞过程和信号传导途径。Syndecan-4 与这些相互作用伙伴之间复杂的相互作用强调了其在细胞表面的多功能作用，表明对外泌体动力学和其他细胞活动的潜在贡献。

Measured by its binding ability in a functional ELISA. Immobilized Syndecan-4 at 500ng/mL (100μL/well) can bind bFGF (HY-P7331A). The ED₅₀ for this effect is 7.830 ng/mL.

Human

E. coli

Tag Free

P31431-1 (E19-E145)

6385  [NCBI]

ESIRETEVIDPQDLLEGRYFSGALPDDEDVVGPGQESDDFELSGSGDLDDLEDSMIGPEVVHPLVPLDNHIPERAGSGSQVPTEPKKLEENEVIPKRISPVEESEDVSNKVSMSSTVQGSNIFERTE

Approximately 24 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末.

Lyophilized from a 0.2 μm solution of PBS, pH 7.4, 8% trehalose.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in sterile distilled water.

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.