2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  3. ROR
  4. RORγt inverse agonist 31

RORγt inverse agonist 31 (14g) 是一种有效的视黄酸受体相关孤儿受体 γt (RORγt) 反向激动剂，IC50 为 0.428 μM。RORγt inverse agonist 31 (14g) 可以减轻 Imiquimod (HY-B0180) 诱导的小鼠牛皮癣的严重程度。

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RORγt inverse agonist 31 Chemical Structure

RORγt inverse agonist 31 Chemical Structure

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RORγt inverse agonist 31 相关抗体

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生物活性

RORγt inverse agonist 31 (14g) is a potent retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonist, with an IC50 of 0.428 μM. RORγt inverse agonist 31 can alleviate the severity of Imiquimod (HY-B0180)-induced psoriasis in mice[1].

IC50 & Target

IC50: 0.428 μM (RORγt)[1]
分子量

555.36

Formula

C23H15Cl2F3N4O3S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

RORγt inverse agonist 31 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RORγt inverse agonist 31RORγt inverse agonist31RORγt inverse agonist-31RORRAR-related orphan receptorImiquimodpsoriasisInhibitorinhibitorinhibit

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产品名称：
RORγt inverse agonist 31
目录号：
HY-155548
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