1. Anti-infection
  2. Bacterial
  3. RT2

RT2 是一种富含色氨酸的阳离子两亲性抗菌肽,主要靶点包括细菌表面的脂多糖 (LPS) 以及细胞内的 DNA。RT2 通过与细菌表面 LPS 结合,与细胞质膜磷脂相互作用,促使自身快速穿透细菌细胞膜进入细胞内,然后与 DNA 等细胞质膜成分结合,进而发挥抗菌作用。RT2 有望用于浮游细菌引起的急性和慢性感染的研究。

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Custom Peptide Synthesis

RT2 Chemical Structure

RT2 Chemical Structure

CAS No. : 1539295-33-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

RT2 is a tryptophan-rich cationic amphipathic antibacterial peptide, with main targets including lipopolysaccharide (LPS) on the bacterial surface and intracellular DNA. RT2 binds to bacterial surface LPS, and interacts with cytoplasmic membrane phospholipids, enabling it to rapidly penetrate the bacterial cell membrane and enter the cell, and then bind to components such as DNA in the cytoplasmic membrane, thereby exerting antibacterial effects. RT2 is promising for research of acute and chronic infections caused by planktonic bacteria[1].

分子量

2545.91

Formula

C126H165N39O20

CAS 号
Sequence

Asn-Gly-Val-Gln-Pro-Lys-Tyr-Arg-Trp-Trp-Arg-Trp-Trp-Arg-Arg-Trp-Trp-NH2

Sequence Shortening

NGVQPKYRWWRWWRRWW-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
RT2
目录号:
HY-P10970
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