1. Screening Libraries
  2. CNS-Penetrant Compound Library

CNS-Penetrant Compound Library

Cat. No.: HY-L028
Library Contents: XLSX PDF

A unique collection of 323 bioactive CNS-penetrant compounds for high throughput screening (HTS) and high content screening (HCS).

Size (Pre-dissolved DMSO or Solid) Price Stock
30 μL/well (10 mM solution) Get quote In-stock
50 μL/well (10 mM solution) Get quote In-stock
100 μL/well (10 mM solution) Get quote In-stock
250 μL/well (10 mM solution) Get quote In-stock

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  • Description

  • Product Details

  • Composition

  • Contents

  • Documentation

Description
& Advantages

•   A unique collection of 323 bioactive CNS-penetrant compounds for high throughput screening (HTS) and high content screening (HCS).

•   Targets such as Kinases, GPCR and Ion Channels, and more.

•   A useful tool for the discovery of drugs used for brain diseases, such as brain tumors, mental disorders, and neurodegenerative diseases.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some inhibitors have been approved by FDA.

•   Structurally diverse, medicinally active, CNS-penetrant and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 323 CNS-penetrant compounds supplied as pre-dissolved DMSO solutions or Solid
Container:
96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Composition

CNS-Penetrant Compound Library

Source: MedChem Express

Contents of CNS-Penetrant Compound Library

Plate layout: HY-L028-1

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Pimavanserin tartrate L-Cycloserine D-Cycloserine Vinorelbine (ditartrate) Cyclosporin A Pyrazinamide Cisatracurium (besylate) Flucytosine Vigabatrin Vitamin B12 Empty
b Empty Isoniazid Salicylic acid Tramiprosate Choline (chloride) Ethosuximide Trimethadione Dimethyl fumarate Valproic acid Penicillamine Tranexamic acid Empty
c Empty Acetylcysteine Metformin (hydrochloride) Ethionamide 5-Aminolevulinic acid (hydrochloride) Chlorzoxazone Levetiracetam Metronidazole Gabapentin Edaravone Fosfomycin (calcium) Empty
d Empty Theophylline Aspirin Acetylcholine (chloride) Tranylcypromine (hemisulfate) Sodium phenylbutyrate Amantadine (hydrochloride) Antipyrine Temozolomide Halothane Acamprosate (calcium) Empty
e Empty 4-Aminoantipyrine (R)-(-)-Ibuprofen Ibuprofen RJR-2403 (hemioxalate) Zonisamide Serotonin hydrochloride Baclofen Memantine (hydrochloride) Primidone Metaxalone Empty
f Empty Acetazolamide Stavudine Acyclovir Lamivudine Melatonin Lomustine Riluzole Phenelzine (sulfate) Lidocaine Didanosine Empty
g Empty Carbamazepine Dexmedetomidine (hydrochloride) Rufinamide Felbamate Methocarbamol Cytarabine Ribavirin Flurbiprofen (R)-Flurbiprofen Veliparib Empty
h Empty Etomidate Busulfan Emtricitabine Pyrimethamine Rivastigmine Oxcarbazepine Phenytoin Sulfamethoxazole Daidzein S-(+)-Ketoprofen Empty

Plate layout: HY-L028-2

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Ketoprofen Ganciclovir Miglustat (hydrochloride) Lamotrigine sn-Glycero-3-phosphocholine Procarbazine (Hydrochloride) Thalidomide Salsalate Lenalidomide Ramelteon Empty
b Empty Pyridostigmine (bromide) Vorinostat Mirtazapine Nevirapine Atenolol Clonidine (hydrochloride) Zidovudine Adenosine Rasagiline (mesylate) Diethylstilbestrol Empty
c Empty Genistein Lidocaine (hydrochloride) Tolcapone Pomalidomide Phenytoin (sodium) Rolipram Bupropion (hydrochloride) Sulfamethoxypyridazine Etomidate (hydrochloride) Guanfacine (hydrochloride) Empty
d Empty Milnacipran (hydrochloride) Milnacipran ((1S-cis) hydrochloride) Pramipexole (dihydrochloride) Oseltamivir (acid) Probenecid Cladribine Abacavir Tenofovir Etodolac Galanthamine Empty
e Empty Zolmitriptan Terbinafine BSI-201 Propranolol (hydrochloride) Diclofenac Disulfiram Ropinirole (hydrochloride) Metoclopramide Protriptyline (hydrochloride) Nortriptyline (hydrochloride) Empty
f Empty Retinoic acid Desipramine hydrochloride Chlorambucil Clioquinol Fluconazole Fingolimod Phenylbutazone Cyclobenzaprine (hydrochloride) Olanzapine Molindone (hydrochloride) Empty
g Empty Amoxapine Amitriptyline (hydrochloride) Venlafaxine (hydrochloride) Rofecoxib Progesterone Rotigotine Efavirenz Pregnenolone Imipramine (hydrochloride) Tetrabenazine Empty
h Empty Diclofenac (Sodium) Cytosporone B Cyproheptadine (hydrochloride) Quinidine Bupivacaine (hydrochloride) Dyclonine (hydrochloride) Clozapine Loxapine Piroxicam Palonosetron (Hydrochloride) Empty

Plate layout: HY-L028-3

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Trihexyphenidyl (hydrochloride) Topiramate Liproxstatin-1 Sulpiride Sertraline (hydrochloride) Fingolimod (hydrochloride) Testosterone (propionate) Fluoxetine (hydrochloride) L-779450 Granisetron (Hydrochloride) Empty
b Empty Voriconazole Clomipramine (hydrochloride) Meloxicam Roscovitine Sulindac Laquinimod Rosiglitazone Oxybutynin Indomethacin Prednisone Empty
c Empty Capecitabine Prednisolone Ofloxacin Levofloxacin L-701324 SC79 NS 1738 SRI-011381 (hydrochloride) MRK-016 SB 239063 Empty
d Empty Tamoxifen Naratriptan (hydrochloride) Methylprednisolone Gatifloxacin Haloperidol Ketorolac (tromethamine salt) Naltrexone (Hydrochloride) Droperidol SB-222200 SNS-032 Empty
e Empty GTS-21 (dihydrochloride) Loratadine Quetiapine Amoxicillin (sodium) Doxylamine (succinate) SB-269970 (hydrochloride) Alfuzosin Rizatriptan (benzoate) Dexamethasone Erlotinib Empty
f Empty Bendamustine (hydrochloride) Sulfasalazine Sunitinib Desvenlafaxine (succinate hydrate) Dantrolene (sodium hemiheptahydrate) Rivastigmine (tartrate) Flavopiridol Prednisolone (21-acetate) Benztropine (mesylate) Perphenazine Empty
g Empty Lovastatin Fosphenytoin (disodium) NGP555 Thioridazine (hydrochloride) Trazodone (hydrochloride) Trimipramine (maleate) Tiagabine (hydrochloride) Sumatriptan (succinate) Escitalopram (oxalate) GNE-317 Empty
h Empty Mefloquine (hydrochloride) Nimodipine Simvastatin Amoxicillin (trihydrate) Vatalanib (dihydrochloride) Vismodegib Buspirone (hydrochloride) Trimethobenzamide hydrochloride Domperidone Iloperidone Empty

Plate layout: HY-L028-4

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Paliperidone Erlotinib (Hydrochloride) Fluvoxamine (maleate) Olaparib Dexamethasone (acetate) Aztreonam AK-7 Pazopanib Flavopiridol (Hydrochloride) Candesartan Empty
b Empty AEE788 Vilazodone Debio 0932 Gefitinib Hydroxyzine (dihydrochloride) Aripiprazole Cediranib SB-590885 Methotrexate (+)-JQ-1 Empty
c Empty Selumetinib Topotecan (Hydrochloride) AZD3759 Orphenadrine (citrate) Sorafenib Ziprasidone (hydrochloride monohydrate) Almotriptan (malate) Dacomitinib Pazopanib (Hydrochloride) Vandetanib Empty
d Empty Givinostat (hydrochloride monohydrate) Cefotaxime (sodium salt) Miconazole (nitrate) Trifluoperazine (dihydrochloride) Palbociclib (hydrochloride) Dasatinib Glibenclamide Firategrast Amprenavir Nefazodone (hydrochloride) Empty
e Empty Fluphenazine (dihydrochloride) Enzastaurin Nicardipine (Hydrochloride) Pemetrexed (disodium hemipenta hydrate) SRT 2104 Probucol Vardenafil (hydrochloride) Aprepitant Conivaptan (hydrochloride) Piperacillin (sodium) Empty
f Empty Ceftazidime Delavirdine (mesylate) VER-155008 Mezlocillin (sodium) Tandutinib Tamoxifen (Citrate) Cefepime (Dihydrochloride Monohydrate) Palbociclib (isethionate) Atorvastatin (hemicalcium salt) Epirubicin (hydrochloride) Empty
g Empty Lapatinib Irinotecan Cilengitide Imatinib (Mesylate) Hoechst 34580 (tetrahydrochloride) Ceftriaxone (sodium salt) Candesartan (Cilexetil) GNE-7915 (tosylate) Lopinavir Sorafenib (Tosylate) Empty
h Empty Lonafarnib Abacavir (sulfate) Irinotecan (hydrochloride trihydrate) Dihydroergotamine (mesylate) Itraconazole Ritonavir Streptomycin (sulfate) Hydroxyurea Atazanavir (sulfate) Rifampicin Empty

Plate layout: HY-L028-5

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Cabazitaxel Vincristine (sulfate) Lapatinib (ditosylate) Empty Empty Empty Empty Empty Empty Empty Empty
b Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
c Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
d Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
e Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
f Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
g Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
h Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
Documentation

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CNS-Penetrant Compound Library
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