2. Others Metabolic Enzyme/Protease Epigenetics
  3. Isotope-Labeled Compounds Endogenous Metabolite Histone Demethylase
  4. Sodium 2-hydroxypentanedioate-2,3,3-d3

Sodium 2-hydroxypentanedioate-2,3,3-d3 

目录号: HY-W704805
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Sodium 2-hydroxypentanedioate-2,3,3-d3 是 α-Hydroxyglutaric acid disodium (HY-113038A) 的氘代物。α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium 是戊二酸的 α-羟基酸形式。α-Hydroxyglutaric acid disodium 是多种 α-酮戊二酸依赖性双加氧酶 (包括 histone demethylases 和 5-甲基胞嘧啶羟化酶 (5-methlycytosine (5mC) hydroxylases) 的 TET 家族) 的竞争性抑制剂。

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Sodium 2-hydroxypentanedioate-2,3,3-d<sub>3</sub> Chemical Structure

Sodium 2-hydroxypentanedioate-2,3,3-d3 Chemical Structure

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Sodium 2-hydroxypentanedioate-2,3,3-d3 相关抗体

Top Publications Citing Use of Products

查看 Histone Demethylase 亚型特异性产品:

查看所有亚型
KDM1/LSD1 KDM2 KDM3 KDM4 KDM5 KDM6 KDM7

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sodium 2-hydroxypentanedioate-2,3,3-d3 is the deuterium labeled α-Hydroxyglutaric acid disodium (HY-113038A). α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[1].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Sodium 2-hydroxypentanedioate-2,3,3-d3 相关抗体:
分子量

195.10

Formula

C5H3D3Na2O5
非标记 CAS
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Sodium 2-hydroxypentanedioate-2,3,3-d3 相关分类

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Keywords:

Sodium 2-hydroxypentanedioate-2,3,3-d3Isotope-Labeled CompoundsEndogenous MetaboliteHistone DemethylaseInhibitorinhibitorinhibit

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