1. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  2. Reactive Oxygen Species (ROS)
  3. Sulforaphane-d8

Sulforaphane-d8  (Synonyms: 萝卜硫素-d8)

目录号: HY-W701218
产品使用指南 技术支持

Sulforaphane-d8Sulforaphane (HY-13755) 的氘代物。Sulforaphane 是一种具有口服活性的 Keap1/Nrf2/ARE 诱导剂。Sulforaphane 能促进肿瘤抑制蛋白的转录,并有效地抑制 HDACs 的活性。Sulforaphane 通过激活 Keap1/Nrf2/ARE 途径,以及进一步诱导 HO-1 的表达保护心脏。Sulforaphane 通过 AMPK 依赖性信号传导抑制高糖诱导的胰腺癌。Sulforaphane 具有抗癌和抗炎活性。

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Sulforaphane-d<sub>8</sub> Chemical Structure

Sulforaphane-d8 Chemical Structure

CAS No. : 836682-32-7

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Other Forms of Sulforaphane-d8:

  • 生物活性

  • 纯度 & 产品资料

生物活性

Sulforaphane-d8 is the deuterium labeled Sulforaphane (HY-13755). Sulforaphane is an orally active inducer of the Keap1/Nrf2/ARE pathway. Sulforaphane promotes the transcription of tumor-suppressing proteins and effectively inhibits the activity of HDACs. Through the activation of the Keap1/Nrf2/ARE pathway and further induction of HO-1 expression, Sulforaphane protects the heart. Sulforaphane suppresses high glucose-induced pancreatic cancer through AMPK-dependent signal transmission. Sulforaphane exhibits both anticancer and anti-inflammatory properties[1][2][3][4][5][6].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

185.34

Formula

C6H3D8NOS2

CAS 号
非标记 CAS
中文名称

萝卜硫素-d8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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