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  2. TAK-448 acetate

TAK-448 acetate (Synonyms: MVT-602 (acetate))

目录号: HY-P0076A
产品使用指南

TAK-448 acetate (MVT-602 acetate) 是一种有效的 KISS1R 激动剂,IC50 值为 460 pM,EC50 值为 632 pM。

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TAK-448 acetate Chemical Structure

TAK-448 acetate Chemical Structure

CAS No. : 1470374-22-1

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1 mg ¥1500 In-stock
5 mg ¥4500 In-stock
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Description

TAK-448 acetate (MVT-602 acetate) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM[1].

IC50 & Target

IC50: 460 pM (KISS1R)[1]
EC50: 632 pM (KISS1R)[1]

In Vivo

TAK-448 acetate (0.01-3 mg/kg; given i.h.; dosings on day 0 and 28) has greater anti-tumor effects in VCaP xenograft model[2].

Animal Model: Rat VCaP xenograft androgen-sensitive prostate cancer model (7-week-old rats)
Dosage: 0.01, 0.03, 0.3, 3 mg/kg
Administration: Given i.h.; dosings on day 0 and 28
Result: Had greater anti-tumor effects in VCaP xenograft model.
Storage
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
References
Molecular Weight

1285.41

Formula

C₆₀H₈₄N₁₆O₁₆

CAS No.

1470374-22-1

Sequence

Ac-D-Tyr-D-Trp-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2

Sequence Shortening

Ac-Y-{Hyp}-NTFGLRW-NH2

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
TAK-448 acetate
目录号:
HY-P0076A
需求量:

TAK-448 acetate

Cat. No.: HY-P0076A