产品详情

Biological activity

•   Contains 4 or more atoms of halogen (mostly Cl and F).

•   Has S-containing aliphatic/aromatic ring.

•   Contains polar, heteroatom-rich functional groups (e.g. diacyl hydrazines, N-acyl urea etc.), oxazole/oxazoline rings, cyclopropanes, O-containing aliphatic rings.

•   No alcohols, primary amines and secondary amines occur less frequently in agrochemicals.

•   No reactive/toxicophore groups (internal medchem filters). At the same time some compounds bearing active halogen (e.g. 2-chloropyridne) were left in the library.

•   "Trivial” scaffolds and chemotypes.

•   Acidic groups (e.g. carboxylic acids, acylsulfonamides etc.)

•   Fsp³-rich molecules.

•   Unusual/unique chemotypes/scaffolds/combination of cycles.

•   Databases and compounds are provided by Enamine.