2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. Deltorphin I

Deltorphin I  (Synonyms: Deltorphin 1; Deltorphin C)

目录号: HY-P1336 纯度: 99.13%
COA 产品使用指南

摩尔计算器

Deltorphin I 是一种高亲和力的选择性 δ-阿片受体 (δ-opioid receptor) 激动剂。

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Custom Peptide Synthesis

Deltorphin I Chemical Structure

Deltorphin I Chemical Structure

CAS No. : 122752-15-2

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3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥800
In-stock
5 mg ￥2000
In-stock
10 mg ￥3100
In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Customer Review

Deltorphin I 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Deltorphin I is a δ-opioid receptor agonist with high affinity and selectivity.

IC50 & Target

δ-opioid receptor[1]
体内研究
(In Vivo)

Twice daily administration of Deltorphin I (20μg/mouse) for 4 days produces tolerance to Deltorphin I analgesia, as shown by the decrease in the analgesic response. The peak analgesic response to Deltorphin I (20 μg/mouse) at 10 min after injections is decreased from 8.36±0.28 s (the 1st day) to 4.53±0.14 s (the 4th day) markedly. Concurrent treatment of Melatonin (0.5, 1 and 2.5 mg/kg) and Deltorphin I (20 μg/mouse) twice daily for 4 days can attenuate the tolerance to Deltorphin I analgesia (P<0.05, <0.05 and <0.05), and this effect is dose dependent[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

768.86

Formula

C37H52N8O10
CAS 号
性状

固体

颜色

White to off-white

Sequence

Tyr-{d-Ala}-Phe-Asp-Val-Val-Gly-NH2
Sequence Shortening

Y-{d-Ala}-FDVVG-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

DMSO 中的溶解度 : 25 mg/mL (32.52 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.3006 mL 6.5031 mL 13.0063 mL
5 mM 0.2601 mL 1.3006 mL 2.6013 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献
Animal Administration
[1]

Mice[1]
Male Kunming mice (20.0±1.0 g) are used. In order to investigate the chronic effect of Melatonin on opioid receptor agonist analgesia, 18, 17, 16 and 21 mice are treated with Melatonin (0, 0.5, 1 and 2.5 mg/kg, respectively) twice daily for 4 days. On the 5th day, 8, 8, 8 and 9 mice are administered with Endomorphin-1 18 μg/mouse (corresponding to 0, 0.5, 1 and 2.5 mg/kg Melatonin, respectively), while 10, 9, 8 and 12 mice are administered with Deltorphin I 20 μg/mouse (corresponding to 0, 0.5, 1 and 2.5 mg/kg Melatonin, respectively). Subsequently tail-flick latency is measured at 10 min interval within 60 min[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

Deltorphin I 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3006 mL 6.5031 mL 13.0063 mL 32.5157 mL
5 mM 0.2601 mL 1.3006 mL 2.6013 mL 6.5031 mL
10 mM 0.1301 mL 0.6503 mL 1.3006 mL 3.2516 mL
15 mM 0.0867 mL 0.4335 mL 0.8671 mL 2.1677 mL
20 mM 0.0650 mL 0.3252 mL 0.6503 mL 1.6258 mL
25 mM 0.0520 mL 0.2601 mL 0.5203 mL 1.3006 mL
30 mM 0.0434 mL 0.2168 mL 0.4335 mL 1.0839 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Deltorphin I122752-15-2Deltorphin 1 Deltorphin CDeltorphin1Deltorphin-1Opioid ReceptorInhibitorinhibitorinhibit

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