1. Immunology/Inflammation
  2. NO Synthase

NO Synthase

Nitric oxide synthases (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine. NO synthases catalyze the oxidation of L-arginine to NO and L-citrulline. Mammals contain three NOS isoforms: neuronal NOS (nNOS), inducible NOS (iNOS), and endothelial NOS (eNOS). NO produced from these different NOS isoforms is involved in a wide range of physiologic functions in the nervous, immune, and cardiovascular systems. Unregulated NO production can lead to pathologic conditions such as stroke, inflammation, and hypertension. Therefore, the control of NOS activity by isoform selective NOS inhibitors has great potential for therapeutic treatments of NO-related diseases.

NO Synthase 相关产品 (7):

Cat. No. Product Name Effect Purity
  • HY-N0455A
    L-Arginine hydrochloride Activator >98.0%
    L-Arginine盐酸盐为合成一氧化氮的氮供体,是血管扩张剂。
  • HY-18731
    1400W Dihydrochloride Inhibitor >98.0%
    1400W dihydrochloride是高效,选择性的诱导型一氧化氮合成酶 (NO synthase) 抑制剂,Ki 值为7 nM。
  • HY-19504
    AVE-3085 Activator
    AVE-3085 是一种有效的 nitric oxide synthase 增强剂,常用于治疗心血管疾病。
  • HY-N0455
    L-Arginine Activator
    L-Arginine为合成一氧化氮的氮供体,是血管扩张剂。
  • HY-102015
    6-Biopterin 98.02%
    6-Biopterin (L-Biopterin),一种蝶呤衍生物,是一氧化氮合酶 (NO synthase) 辅因子。
  • HY-N2300
    Kuwanon A Inhibitor
    Kuwanon A是从桑树 (Morus alba L.) 的根皮中分离的的黄酮衍生物,抑制一氧化氮产生的IC50值为10.5 μM。
  • HY-101238
    Agmatine sulfate Inhibitor >98.0%
    Agmatine sulfate在多个靶点上发挥调节作用,如神经递质系统,离子通道,一氧化氮合成。它是 imidazoline receptor 的内源性激动剂和 NO synthase 抑制剂。