1. Inhibitory Antibodies
  2. Briquilimab

Briquilimab  (Synonyms: JSP-191)

目录号: HY-P99488 纯度: 96.57%
COA

Briquilimab (JSP-191) 是一种无毒的人源化单克隆抗体,靶向 CD117 (c-Kit),用于耗尽造血干细胞 (HSC)。Briquilimab 作为重度联合免疫缺陷 (SCID) 的主要方法,可清除宿主骨髓生态位空间,实现足够的供体造血干细胞移植和免疫重建。

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Briquilimab Chemical Structure

Briquilimab Chemical Structure

CAS No. : 2574591-89-0

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     可免费申领三个不同产品的试用装。

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规格 价格 是否有货 数量
1 mg ¥2500
In-stock
5 mg ¥5600
In-stock
10 mg ¥8900
In-stock
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100 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Briquilimab (JSP-191) is a non-toxic humanized monoclonal antibody targeting CD117 (c-Kit) to deplete hematopoietic stem cell (HSC). Briquilimab has safety to clear host marrow niche space to enable sufficient donor HSC engraftment and immune reconstitution as primary method of severe combined immunodeficiency (SCID)[1].

IC50 & Target

CD117 (c-Kit)[1]

Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Briquilimab
目录号:
HY-P99488
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