1. Gene
  2. Id4 - inhibitor of DNA binding 4 Gene

Id4 - inhibitor of DNA binding 4 Gene

种属: Mus musculus

同用名: Idb4; bHLHb27

基因 ID: 15904 | 基因类型: protein coding

关于 Id4

功能概要

Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Acts upstream of or within several processes, including gland morphogenesis; neurogenesis; and regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; immune system; sensory organ; and urinary system. Used to study osteoporosis. Orthologous to human ID4 (inhibitor of DNA binding 4, HLH protein). [provided by Alliance of Genome Resources, Apr 2022]

Id4 基因产物(1)

mRNA Protein Name
NM_031166.3 NP_112443.1 DNA-binding protein inhibitor ID-4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
20628571 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15280210 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within G1/S transition of mitotic cell cycle IMP
IMP: 通过突变表型推断
15469968 MGI
acts upstream of astrocyte differentiation IGI
IGI: 通过遗传相互作用推断
15882580 MGI
acts upstream of or within brain development IMP
IMP: 通过突变表型推断
15469968 MGI
acts upstream of cell population proliferation IMP
IMP: 通过突变表型推断
15469968 MGI
acts upstream of or within central nervous system myelination IMP
IMP: 通过突变表型推断
16862533 MGI
acts upstream of or within cerebral cortex neuron differentiation IMP
IMP: 通过突变表型推断
15469968 MGI
involved in circadian rhythm IEP
IEP: 通过表达模式推断
19217292 MGI
acts upstream of fat cell differentiation IMP
IMP: 通过突变表型推断
20628571 MGI
acts upstream of or within fat cell differentiation IMP
IMP: 通过突变表型推断
20460371 MGI
acts upstream of or within hippocampus development IMP
IMP: 通过突变表型推断
15469968 MGI
acts upstream of or within negative regulation of astrocyte differentiation IGI
IGI: 通过遗传相互作用推断
15882580 MGI
acts upstream of or within negative regulation of fat cell differentiation IMP
IMP: 通过突变表型推断
20628571 MGI
acts upstream of or within negative regulation of neuron differentiation IMP
IMP: 通过突变表型推断
15882580 MGI
acts upstream of or within negative regulation of oligodendrocyte differentiation IMP
IMP: 通过突变表型推断
16862533 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
16862533 MGI
acts upstream of neuroblast proliferation IMP
IMP: 通过突变表型推断
15882580 MGI
acts upstream of or within neuroblast proliferation IMP
IMP: 通过突变表型推断
15882580 MGI
acts upstream of neuron differentiation IMP
IMP: 通过突变表型推断
15882580 MGI
acts upstream of oligodendrocyte differentiation IMP
IMP: 通过突变表型推断
16862533 MGI
acts upstream of or within osteoblast differentiation IMP
IMP: 通过突变表型推断
20628571 MGI
acts upstream of or within positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
15469968 MGI
acts upstream of or within positive regulation of gene expression IMP
IMP: 通过突变表型推断
23786676 MGI
acts upstream of or within positive regulation of neuroblast proliferation IMP
IMP: 通过突变表型推断
15882580 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
20628571 MGI
acts upstream of or within prostate gland epithelium morphogenesis IMP
IMP: 通过突变表型推断
23786676 MGI
acts upstream of or within prostate gland morphogenesis IMP
IMP: 通过突变表型推断
23786676 MGI
acts upstream of or within prostate gland stromal morphogenesis IMP
IMP: 通过突变表型推断
23786676 MGI
acts upstream of or within protein localization IMP
IMP: 通过突变表型推断
16862533 MGI
acts upstream of or within seminal vesicle morphogenesis IMP
IMP: 通过突变表型推断
23786676 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
9418957 MGI
located in nucleus IDA
IDA: 通过直接分析推断
9418957 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

DNA-binding protein inhibitor ID-4

inhibitor of differentiation 4

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Id4 NCBI NCBI:3400
Macaca fascicularis Id4 NCBI NCBI:102139121