1. Gene
  2. Sgk3 - serum/glucocorticoid regulated kinase 3 Gene

Sgk3 - serum/glucocorticoid regulated kinase 3 Gene

中文名称:血清/糖皮质激素调节激酶 3

种属: Mus musculus

同用名: fy; fz; Cisk; 2510015P22Rik; A330005P07Rik

基因 ID: 170755 | 基因类型: protein coding

关于 Sgk3

Chromosome 1: 9,868,332-9,971,070 forward strand.GRCm39:CM000994.3

This gene has 12 transcripts (splice variants), 212 orthologues, 13 paralogues and is associated with 44 phenotypes. Broad expression in placenta adult (RPKM 7.), liver E14 (RPKM 4.9) and 19 other tissues.

功能概要

该基因编码的蛋白可启动蛋白质丝氨酸/苏氨酸激酶活性。在没有配体的情况下,作用于外在凋亡信号通路的负调节上游或负调节内。位于细胞质囊泡中。以多种结构表达,包括消化系统;脑;泌尿生殖系统;呼吸系统;和感觉器官。与几个人类基因同源,包括 C8orf44-SGK3(C8orf44-SGK3 通读)。 [由基因组资源联盟提供,2022 年 4 月]

Enables protein serine/threonine kinase activity. Acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway in absence of ligand. Located in cytoplasmic vesicle. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to several human genes including C8orf44-SGK3 (C8orf44-SGK3 readthrough). [provided by Alliance of Genome Resources, Apr 2022]

Sgk3 基因产物(3)

mRNA Protein Name
NM_133220.2 NP_573483.1 serine/threonine-protein kinase Sgk3
NM_001037759.1 NP_001032848.1 serine/threonine-protein kinase Sgk3
NM_177547.3 NP_808215.2 serine/threonine-protein kinase Sgk3

Sgk3 蛋白结构

PX_CISK

PX_CISK: cd06870 (11 - 119)

STKc_SGK3

STKc_SGK3: cd05604 (164 - 489)

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  • 496 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase Sgk3

cytokine-independent survival kinase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sgk3 NCBI NCBI:23678