2. Gene
  3. Ash1l - ASH1 like histone lysine methyltransferase Gene

Ash1l - ASH1 like histone lysine methyltransferase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ash1; Kmt2h; 8030453L17Rik; E430018P19Rik

基因 ID: 192195 | 基因类型: protein coding

关于 Ash1l

功能概要

Enables Histone Methyltransferase activity (H3-K4 specific) and Histone Methyltransferase activity (H3-K9 specific). Acts upstream of or within several processes, including negative regulation of intracellular signal transduction; reproductive structure development; and tarsal gland development. Predicted to be located in Golgi apparatus and nucleoplasm. Is expressed in early conceptus; inner cell mass; oocyte; and ureter. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 52. Orthologous to human ASH1L (ASH1 like histone lysine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Ash1l 基因产物(1)

mRNA Protein Name
NM_138679.5 NP_619620.3 histone-lysine N-methyltransferase ASH1L
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone H3K4 methyltransferase activity IDA
IDA: 通过直接分析推断
24012418 MGI
enables histone H3K4 methyltransferase activity IMP
IMP: 通过突变表型推断
24012418 MGI
enables histone H3K9 methyltransferase activity IDA
IDA: 通过直接分析推断
22939622 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of MAPK cascade IMP
IMP: 通过突变表型推断
24012418 MGI
acts upstream of or within decidualization IMP
IMP: 通过突变表型推断
26333994 MGI
acts upstream of or within flagellated sperm motility IMP
IMP: 通过突变表型推断
26333994 MGI
acts upstream of inflammatory response IGI
IGI: 通过遗传相互作用推断
24012418 MGI
acts upstream of or within interleukin-6 production IGI
IGI: 通过遗传相互作用推断
24012418 MGI
acts upstream of or within macrophage cytokine production IGI
IGI: 通过遗传相互作用推断
24012418 MGI
acts upstream of or within negative regulation of MAPK cascade IMP
IMP: 通过突变表型推断
24012418 MGI
acts upstream of or within negative regulation of acute inflammatory response IMP
IMP: 通过突变表型推断
24012418 MGI
acts upstream of or within negative regulation of inflammatory response IGI
IGI: 通过遗传相互作用推断
24012418 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
24012418 MGI
acts upstream of or within post-embryonic development IMP
IMP: 通过突变表型推断
26333994 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
26333994 MGI
acts upstream of or within sebaceous gland development IMP
IMP: 通过突变表型推断
26333994 MGI
acts upstream of or within single fertilization IMP
IMP: 通过突变表型推断
26333994 MGI
acts upstream of or within skeletal system development IMP
IMP: 通过突变表型推断
26333994 MGI
acts upstream of or within tarsal gland development IMP
IMP: 通过突变表型推断
26333994 MGI
acts upstream of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
24012418 MGI
acts upstream of or within uterine gland development IMP
IMP: 通过突变表型推断
26333994 MGI
acts upstream of or within uterus morphogenesis IMP
IMP: 通过突变表型推断
26333994 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

histone-lysine N-methyltransferase ASH1L

ASH1-like protein

absent small and homeotic disks protein 1 homolog

absent, small, or homeotic discs 1

ash1 (absent, small, or homeotic)-like

chromatin remodeling factor

probable histone-lysine N-methyltransferase ASH1L

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-141429A AS-99 TFA 99.15% 否
HY-141430 AS-85 Inhibitor 98.96% 否
HY-141429 AS-99 free base / 否
HY-141429C AS-99 / 否
HY-170494 AS-254s Inhibitor / 否
HY-RS01087 ASH1L Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17758 Ash1l Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24225 Ash1l Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ash1l NCBI NCBI:55870
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