2. Gene
  3. Trib1 - tribbles pseudokinase 1 Gene

Trib1 - tribbles pseudokinase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Trb1; TRB-1; A530090O15Rik

基因 ID: 211770 | 基因类型: protein coding

关于 Trib1

功能概要

Enables ubiquitin protein Ligase binding activity and ubiquitin-protein transferase regulator activity. Involved in several processes, including negative regulation of DNA-binding transcription factor activity; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and regulation of myeloid leukocyte differentiation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart valve; and integumental system. Orthologous to human TRIB1 (tribbles pseudokinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Trib1 基因产物(1)

mRNA Protein Name
NM_144549.4 NP_653132.1 tribbles homolog 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
17724128 MGI
enables ubiquitin protein ligase binding IDA
IDA: 通过直接分析推断
20410507 MGI
enables ubiquitin-protein transferase regulator activity IDA
IDA: 通过直接分析推断
20410507 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
17724128 MGI
involved in negative regulation of neutrophil differentiation IMP
IMP: 通过突变表型推断
23515163 MGI
involved in positive regulation of eosinophil differentiation IMP
IMP: 通过突变表型推断
23515163 MGI
involved in positive regulation of macrophage differentiation IMP
IMP: 通过突变表型推断
23515163 MGI
involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
20410507 MGI
involved in response to lipopolysaccharide IMP
IMP: 通过突变表型推断
17724128 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tribbles homolog 1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-123494 BRD0418 Modulator 99.22% 否
HY-RS15015 TRIB1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22878 Trib1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29392 Trib1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Trib1 NCBI NCBI:10221
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z