2. Gene
  3. Zfpm1 - zinc finger protein, multitype 1 Gene

Zfpm1 - zinc finger protein, multitype 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: FOG; Fog1

基因 ID: 22761 | 基因类型: protein coding

关于 Zfpm1

功能概要

Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including embryonic hemopoiesis; heart development; and negative regulation of cell differentiation. Acts upstream of or within several processes, including myeloid cell differentiation; regulation of chemokine production; and regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and integumental system. Orthologous to human ZFPM1 (Zinc Finger Protein, FOG family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Zfpm1 基因产物(1)

mRNA Protein Name
NM_009569.4 NP_033595.1 zinc finger protein ZFPM1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II-specific DNA-binding transcription factor binding IDA
IDA: 通过直接分析推断
9230307 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9230307 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in atrial septum morphogenesis IMP
IMP: 通过突变表型推断
14614148 MGI
involved in atrioventricular valve morphogenesis IMP
IMP: 通过突变表型推断
14614148 MGI
involved in cardiac muscle tissue morphogenesis IMP
IMP: 通过突变表型推断
14614148 MGI
acts upstream of or within definitive erythrocyte differentiation IMP
IMP: 通过突变表型推断
9553047 MGI
involved in embryonic hemopoiesis IMP
IMP: 通过突变表型推断
14614148 MGI
acts upstream of or within erythrocyte differentiation IGI
IGI: 通过遗传相互作用推断
9230307 MGI
acts upstream of or within erythrocyte differentiation IMP
IMP: 通过突变表型推断
20010697 MGI
acts upstream of or within granulocyte differentiation IMP
IMP: 通过突变表型推断
20010697 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
14614148 MGI
acts upstream of or within homeostasis of number of cells IMP
IMP: 通过突变表型推断
20643340 MGI
acts upstream of or within megakaryocyte development IMP
IMP: 通过突变表型推断
20010697 MGI
acts upstream of or within megakaryocyte differentiation IGI
IGI: 通过遗传相互作用推断
9230307 MGI
acts upstream of or within megakaryocyte differentiation IMP
IMP: 通过突变表型推断
9553047 MGI
involved in mitral valve formation IMP
IMP: 通过突变表型推断
14614148 MGI
involved in negative regulation of mast cell differentiation IDA
IDA: 通过直接分析推断
18063754 MGI
involved in negative regulation of protein binding IDA
IDA: 通过直接分析推断
18063754 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
2906112 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
20010697 MGI
involved in outflow tract morphogenesis IMP
IMP: 通过突变表型推断
14614148 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
9230307 MGI
acts upstream of or within primitive erythrocyte differentiation IMP
IMP: 通过突变表型推断
9553047 MGI
acts upstream of or within regulation of chemokine production IMP
IMP: 通过突变表型推断
20643340 MGI
involved in tricuspid valve formation IMP
IMP: 通过突变表型推断
14614148 MGI
involved in ventricular septum morphogenesis IMP
IMP: 通过突变表型推断
14614148 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
12213678 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

zinc finger protein ZFPM1

FOG-1

Friend of GATA 1

friend of GATA protein 1

Zfpm1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Zfpm1 O35615 Kdm1a Mus musculus Q6ZQ88
Anti Tag CoIP
19654328
种属内
Zfpm1 O35615 Kdm1a Mus musculus Q6ZQ88
TAP
19654328
种属内
Zfpm1 O35615 Tacc3 Mus musculus Q9JJ11
Y2H
15234987
种属内
Zfpm1 O35615 Tacc3 Mus musculus Q9JJ11
NMR
15234987
种属内
Zfpm1 O35615 Tacc3 Mus musculus Q9JJ11
Anti Tag CoIP
15234987
种属内
Zfpm1 O35615 Gata1 Mus musculus P17679
Anti Bait CoIP
19513100
种属内
Zfpm1 O35615 Gata1 Mus musculus P17679
TAP
19654328
种属内
Zfpm1 O35615 Gata1 Mus musculus P17679
Anti Bait CoIP
19654328
种属内
Zfpm1 O35615 Gata1 Mus musculus P17679
Y2H
15234987
种属间
Zfpm1 O35615 GATA1 Homo sapiens P15976
Pull Down
11675338
种属间
Zfpm1 O35615 GATA1 Homo sapiens P15976
Y2H
11675338
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16048 ZFPM1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19759 Zfpm1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26256 Zfpm1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Zfpm1 NCBI NCBI:161882
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