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  2. Sp1 - Sp1 transcription factor Gene

Sp1 - Sp1 transcription factor Gene

种属: Rattus norvegicus

基因 ID: 24790 | 基因类型: protein coding

关于 Sp1

功能概要

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; Histone Acetyltransferase binding activity; and transcription coregulator binding activity. Involved in cellular response to Insulin stimulus and positive regulation of transcription by RNA polymerase II. Located in chromatin and nucleus. Part of protein-DNA complex. Orthologous to human SP1 (Sp1 transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Sp1 基因产物(1)

mRNA Protein Name
NM_012655.2 NP_036787.2 transcription factor Sp1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
26908121 RGD
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IGI
IGI: 通过遗传相互作用推断
10362258 RGD
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP
IMP: 通过突变表型推断
14979875 RGD
enables double-stranded DNA binding IDA
IDA: 通过直接分析推断
10837920 RGD
enables histone acetyltransferase binding IPI
IPI: 通过物理相互作用推断
19765194 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
10393239 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
10837920 RGD
enables transcription coregulator binding IPI
IPI: 通过物理相互作用推断
10362258 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to estrogen stimulus IEP
IEP: 通过表达模式推断
17272396 RGD
involved in cellular response to insulin stimulus IDA
IDA: 通过直接分析推断
26908121 RGD
involved in cellular response to wortmannin IEP
IEP: 通过表达模式推断
17272396 RGD
involved in cellular response to zinc ion starvation IEP
IEP: 通过表达模式推断
21893222 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
26908121 RGD
involved in regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
11457835 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatin IDA
IDA: 通过直接分析推断
26908121 RGD
located in nucleus IDA
IDA: 通过直接分析推断
14979875 RGD
part of protein-DNA complex IDA
IDA: 通过直接分析推断
19765194 RGD
part of protein-DNA complex IPI
IPI: 通过物理相互作用推断
10362258 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

transcription factor Sp1

trans-acting transcription factor 1

Sp1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Sp1 Q01714 Nfya Rattus norvegicus P18576 10393239
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sp1 NCBI NCBI:6667
Macaca fascicularis Sp1 NCBI NCBI:102115996
Mus musculus Sp1 NCBI NCBI:20683
Macaca mulatta Sp1 NCBI NCBI:702710