2. Gene
  3. Lamp2 - lysosomal-associated membrane protein 2 Gene

Lamp2 - lysosomal-associated membrane protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 24944 | 基因类型: protein coding

关于 Lamp2

功能概要

Predicted to enable enzyme binding activity and protein domain specific binding activity. Involved in chaperone-mediated Autophagy. Acts upstream of or within protein targeting to lysosome involved in chaperone-mediated Autophagy. Located in endosome; lysosomal matrix; and lysosomal membrane. Colocalizes with membrane raft. Used to study Danon disease; cholestasis; chronic conjunctivitis; cognitive disorder; and hypertrophic cardiomyopathy. Biomarker of myocardial infarction and sciatic neuropathy. Human ortholog(s) of this gene implicated in Danon disease and hypertrophic cardiomyopathy. Orthologous to human LAMP2 (lysosomal associated membrane protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Lamp2 基因产物(1)

mRNA Protein Name
NM_017068.3 NP_058764.3 lysosome-associated membrane glycoprotein 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12505983 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in chaperone-mediated autophagy IDA
IDA: 通过直接分析推断
11082038 RGD
acts upstream of or within protein targeting to lysosome involved in chaperone-mediated autophagy IGI
IGI: 通过遗传相互作用推断
18644871 RGD
acts upstream of or within protein targeting to lysosome involved in chaperone-mediated autophagy IMP
IMP: 通过突变表型推断
18644871 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endosome IDA
IDA: 通过直接分析推断
16085051 RGD
located in lysosomal matrix IDA
IDA: 通过直接分析推断
18644871 RGD
located in lysosomal membrane IDA
IDA: 通过直接分析推断
8662539 RGD
located in membrane raft IMP
IMP: 通过突变表型推断
20797626 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lysosome-associated membrane glycoprotein 2

CD107 antigen-like family member B

LAMP-2

LGP-110

LGP-96

LGP-B

lysosomal membrane glycoprotein 2

lysosomal membrane glycoprotein type B

lysosome-associated membrane protein 2

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-134923 CA77.1 Inducer 99.98% 否
HY-112483 QX77 Inducer 99.48% 否
HY-RS07510 LAMP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17112 Lamp2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23557 Lamp2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lamp2 NCBI NCBI:3920
Macaca fascicularis Lamp2 NCBI NCBI:102119735
Mus musculus Lamp2 NCBI NCBI:16784
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z