2. Gene
  3. Sarm1 - sterile alpha and TIR motif containing 1 Gene

Sarm1 - sterile alpha and TIR motif containing 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 287545 | 基因类型: protein coding

关于 Sarm1

功能概要

Predicted to enable NAD+ nucleotidase, cyclic ADP-ribose generating and identical protein binding activity. Predicted to be involved in several processes, including NAD catabolic process; positive regulation of neuron death; and regulation of dendrite morphogenesis. Predicted to act upstream of or within regulation of apoptotic process and response to glucose. Predicted to be located in microtubule; mitochondrion; and synapse. Predicted to be extrinsic component of mitochondrial outer membrane. Predicted to be active in dendrite. Orthologous to human SARM1 (sterile alpha and TIR motif containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Sarm1 基因产物(1)

mRNA Protein Name
NM_001105817.1 NP_001099287.1 NAD(+) hydrolase SARM1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in modification of postsynaptic structure IDA
IDA: 通过直接分析推断
21555464 RGD
involved in modification of postsynaptic structure IMP
IMP: 通过突变表型推断
21555464 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in extrinsic component of synaptic membrane IDA
IDA: 通过直接分析推断
21555464 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
21555464 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
21555464 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

NAD(+) hydrolase SARM1

NADP(+) hydrolase SARM1

NADase SARM1

sterile alpha and TIR motif-containing protein 1

相关产品

Approval
生物活性分子 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B0985 Phenazopyridine hydrochloride Antagonist 99.84% 否
HY-B0985A Phenazopyridine Antagonist 99.93% 否
Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-129522 Sulfo-ara-F-NMN Activator 99.36% Phase 1
Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-W021879 DSRM-3716 Inhibitor 99.91% 否
HY-145917 SARM1-IN-2 Inhibitor 99.34% 否
HY-Z0816 Dehydronitrosonisoldipine Antagonist 98.86% 否
HY-112257 S-23 Modulator 99.93% 否
HY-161918 SARM1-IN-3 Inhibitor / 否
HY-172967 SARM1-IN-5 Inhibitor / 否
HY-173276 SARM1-IN-4 Inhibitor / 否
HY-176487 SARM1-IN-6 / 否
HY-RS12446 SARM1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16722 Sarm1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23158 Sarm1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-W008341 5-Chloroisoquinoline Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sarm1 NCBI NCBI:23098
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