1. Gene
  2. F5 - coagulation factor V Gene

F5 - coagulation factor V Gene

种属: Rattus norvegicus

同用名: Ac2-120

基因 ID: 304929 | 基因类型: protein coding

关于 F5

功能概要

Predicted to enable oxidoreductase activity. Involved in blood coagulation and response to vitamin K. Located in Golgi apparatus; endoplasmic reticulum; and extracellular space. Used to study membranoproliferative glomerulonephritis. Biomarker of hepatitis and portal hypertension. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); end stage renal disease; factor V deficiency; liver disease (multiple); and non-arteritic anterior ischemic optic neuropathy. Orthologous to human F5 (coagulation factor V). [provided by Alliance of Genome Resources, Apr 2022]

F5 基因产物(1)

mRNA Protein Name
NM_001047878.1 NP_001041343.1 coagulation factor V
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to vitamin K IEP
IEP: 通过表达模式推断
658784 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
15172885 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
3956160 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

coagulation factor V

coagulation factor V (proaccelerin, labile factor)

直系同源

种属 基因名 来源 基因 ID
Homo sapiens F5 NCBI NCBI:2153
Canis familiaris F5 NCBI NCBI:100685858
Macaca fascicularis F5 NCBI NCBI:102141482
Mus musculus F5 NCBI NCBI:14067
Leporidae F5 NCBI
Macaca mulatta F5 NCBI NCBI:704695