1. Gene
  2. Macf1 - microtubule-actin crosslinking factor 1 Gene

Macf1 - microtubule-actin crosslinking factor 1 Gene

种属: Rattus norvegicus

基因 ID: 362587 | 基因类型: protein coding

关于 Macf1

功能概要

Predicted to enable actin filament binding activity; microtubule minus-end binding activity; and structural molecule activity. Involved in positive regulation of Wnt signaling pathway. Located in membrane. Human ortholog(s) of this gene implicated in lissencephaly 9 with complex brainstem malformation. Orthologous to human MACF1 (microtubule actin crosslinking factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Macf1 基因产物(1)

mRNA Protein Name
NM_001135758.3 NP_001129230.2 microtubule-actin cross-linking factor 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16815997 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of Wnt signaling pathway IMP
IMP: 通过突变表型推断
16815997 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
16815997 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

microtubule-actin cross-linking factor 1

actin cross-linking family 7

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Macf1 NCBI NCBI:23499