2. Gene
  3. SMIM1 - small integral membrane protein 1 (Vel blood group) Gene

SMIM1 - small integral membrane protein 1 (Vel blood group) Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：小整合膜蛋白 1 (Vel 血型)

种属: Homo sapiens

同用名: Vel

基因 ID: 388588 | 基因类型: protein coding

关于 SMIM1

Cytogenetic location: 1p36.32 Genomic coordinates (GRCh38): 1:3,772,749-3,775,956 (from NCBI)

This gene has 4 transcripts (splice variants), 103 orthologues and is associated with 1 phenotype. Broad expression in testis (RPKM 6.7), bone marrow (RPKM 6.0) and 14 other tissues.

功能概要

该基因编码一种参与红细胞形成的小型保守蛋白。编码的蛋白质定位于细胞膜，是 Vel 血型的抗原。可变剪接导致编码相同蛋白质的不同转录变体。[RefSeq 提供，2013 年 12 月]

This gene encodes a small, conserved protein that participates in red blood cell formation. The encoded protein is localized to the cell membrane and is the antigen for the Vel blood group. Alternative splicing results in different transcript variants that encode the same protein. [provided by RefSeq, Dec 2013]

SMIM1 基因产物(4)

mRNA Protein Name
NM_001163724.3 NP_001157196.1 small integral membrane protein 1
NM_001288583.2 NP_001275512.1 small integral membrane protein 1
NM_001379690.1 NP_001366619.1 small integral membrane protein 1
NM_001379691.1 NP_001366620.1 small integral membrane protein 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
23563606 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
23505126 GOA
located in cell surface IMP
IMP: 通过突变表型推断
23563606 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
23563606 GOA
located in plasma membrane IMP
IMP: 通过突变表型推断
26452714 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

small integral membrane protein 1

bloodgroup VEL protein

SMIM1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SMIM1 B2RUZ4 RETREG3 Homo sapiens Q86VR2
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 RETREG3 Homo sapiens Q86VR2
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 RETREG3 Homo sapiens Q86VR2
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 SDC3 Homo sapiens A0A0S2Z4U3
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 SDC3 Homo sapiens A0A0S2Z4U3
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 JAGN1 Homo sapiens Q8N5M9
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 JAGN1 Homo sapiens Q8N5M9
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 JAGN1 Homo sapiens Q8N5M9
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 RELL2 Homo sapiens Q8NC24
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 RELL2 Homo sapiens Q8NC24
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 RELL2 Homo sapiens Q8NC24
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 CISD2 Homo sapiens Q8N5K1
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 CISD2 Homo sapiens Q8N5K1
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 CISD2 Homo sapiens Q8N5K1
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 MFF Homo sapiens Q9GZY8-5
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 MFF Homo sapiens Q9GZY8-5
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 FNDC9 Homo sapiens Q8TBE3
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 FNDC9 Homo sapiens Q8TBE3
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 CD74 Homo sapiens P04233-2
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 CD74 Homo sapiens P04233-2
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 CD74 Homo sapiens P04233-2
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 ASZ1 Homo sapiens Q8WWH4
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 ASZ1 Homo sapiens Q8WWH4
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 ASZ1 Homo sapiens Q8WWH4
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 TMPRSS2 Homo sapiens O15393-2
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 TMPRSS2 Homo sapiens O15393-2
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 TMPRSS2 Homo sapiens O15393-2
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 ZDHHC15 Homo sapiens Q96MV8
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 ZDHHC15 Homo sapiens Q96MV8
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 ZDHHC15 Homo sapiens Q96MV8
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 AQP6 Homo sapiens Q13520
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 AQP6 Homo sapiens Q13520
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 TMEM154 Homo sapiens Q6P9G4
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 TMEM154 Homo sapiens Q6P9G4
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 TMEM154 Homo sapiens Q6P9G4
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 SCN3B Homo sapiens Q9NY72
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 SCN3B Homo sapiens Q9NY72
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 SCN3B Homo sapiens Q9NY72
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 MUC1 Homo sapiens P15941-11
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 MUC1 Homo sapiens P15941-11
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 MUC1 Homo sapiens P15941-11
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 GJA8 Homo sapiens P48165
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 GJA8 Homo sapiens P48165
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 GJA8 Homo sapiens P48165
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 SLC18A1 Homo sapiens P54219-3
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 SLC18A1 Homo sapiens P54219-3
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 SLC18A1 Homo sapiens P54219-3
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 HSD17B13 Homo sapiens Q7Z5P4
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 HSD17B13 Homo sapiens Q7Z5P4
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 HSD17B13 Homo sapiens Q7Z5P4
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 SLC10A6 Homo sapiens Q3KNW5
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 SLC10A6 Homo sapiens Q3KNW5
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 SLC10A6 Homo sapiens Q3KNW5
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 TMEM52B Homo sapiens Q4KMG9
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 TMEM52B Homo sapiens Q4KMG9
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 TMEM52B Homo sapiens Q4KMG9
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 FAM209A Homo sapiens Q5JX71
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 FAM174A Homo sapiens Q8TBP5
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 FAM174A Homo sapiens Q8TBP5
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 FAM174A Homo sapiens Q8TBP5
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 FAM210B Homo sapiens Q96KR6
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 FAM210B Homo sapiens Q96KR6
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 FAM210B Homo sapiens Q96KR6
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 SLC26A11 Homo sapiens Q86WA9
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 SLC26A11 Homo sapiens Q86WA9
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 SLC26A11 Homo sapiens Q86WA9
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 TMEM86B Homo sapiens Q8N661
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 TMEM86B Homo sapiens Q8N661
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 TMEM86B Homo sapiens Q8N661
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 NDUFAF2 Homo sapiens Q8N183
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 NDUFAF2 Homo sapiens Q8N183
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 NDUFAF2 Homo sapiens Q8N183
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 STING1 Homo sapiens Q86WV6
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 STING1 Homo sapiens Q86WV6
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 STING1 Homo sapiens Q86WV6
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 SIGLEC7 Homo sapiens Q9Y286
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 SIGLEC7 Homo sapiens Q9Y286
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 SIGLEC7 Homo sapiens Q9Y286
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 LHFPL5 Homo sapiens Q8TAF8
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 LHFPL5 Homo sapiens Q8TAF8
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 LHFPL5 Homo sapiens Q8TAF8
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 LRP10 Homo sapiens Q7Z4F1
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 LRP10 Homo sapiens Q7Z4F1
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 LRP10 Homo sapiens Q7Z4F1
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 FFAR2 Homo sapiens O15552
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 FFAR2 Homo sapiens O15552
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 FFAR2 Homo sapiens O15552
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 MFSD6 Homo sapiens Q6ZSS7
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 MFSD6 Homo sapiens Q6ZSS7
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 MFSD6 Homo sapiens Q6ZSS7
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 NAALAD2 Homo sapiens Q9Y3Q0
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 NAALAD2 Homo sapiens Q9Y3Q0
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 NAALAD2 Homo sapiens Q9Y3Q0
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 COMT Homo sapiens P21964
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 COMT Homo sapiens P21964
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 COMT Homo sapiens P21964
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 GJB5 Homo sapiens O95377
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 GJB5 Homo sapiens O95377
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 GJB5 Homo sapiens O95377
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 EBP Homo sapiens Q15125
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 EBP Homo sapiens Q15125
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 EBP Homo sapiens Q15125
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 PVR Homo sapiens P15151
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 PVR Homo sapiens P15151
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 PVR Homo sapiens P15151
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 SAR1A Homo sapiens Q9NR31
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 SAR1A Homo sapiens Q9NR31
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 SAR1A Homo sapiens Q9NR31
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 TMEM45B Homo sapiens Q96B21
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 TMEM45B Homo sapiens Q96B21
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 TMEM45B Homo sapiens Q96B21
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 LRRC4C Homo sapiens Q9HCJ2
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 LRRC4C Homo sapiens Q9HCJ2
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 LRRC4C Homo sapiens Q9HCJ2
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 HACD2 Homo sapiens Q6Y1H2
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 HACD2 Homo sapiens Q6Y1H2
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 HACD2 Homo sapiens Q6Y1H2
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 TMX2 Homo sapiens Q9Y320
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 TMX2 Homo sapiens Q9Y320
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 TMX2 Homo sapiens Q9Y320
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 TM4SF19 Homo sapiens Q96DZ7
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 TM4SF19 Homo sapiens Q96DZ7
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 TM4SF19 Homo sapiens Q96DZ7
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 CREB3L1 Homo sapiens Q96BA8
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 CREB3L1 Homo sapiens Q96BA8
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 BIK Homo sapiens Q13323
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 BIK Homo sapiens Q13323
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 BIK Homo sapiens Q13323
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 ANKS6 Homo sapiens Q68DC2
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 ANKS6 Homo sapiens Q68DC2
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 ANKS6 Homo sapiens Q68DC2
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 STX1A Homo sapiens Q16623
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 STX1A Homo sapiens Q16623
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 STX1A Homo sapiens Q16623
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 ICAM3 Homo sapiens P32942
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 ICAM3 Homo sapiens P32942
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 ICAM3 Homo sapiens P32942
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 TMEM51 Homo sapiens Q9NW97
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 TMEM51 Homo sapiens Q9NW97
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 TMEM51 Homo sapiens Q9NW97
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 BCL2L13 Homo sapiens Q9BXK5
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 BCL2L13 Homo sapiens Q9BXK5
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 BCL2L13 Homo sapiens Q9BXK5
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 REEP4 Homo sapiens Q9H6H4
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 REEP4 Homo sapiens Q9H6H4
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 REEP4 Homo sapiens Q9H6H4
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 ERGIC3 Homo sapiens Q9Y282
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 ERGIC3 Homo sapiens Q9Y282
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 ERGIC3 Homo sapiens Q9Y282
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 KIR2DL3 Homo sapiens P43628
Validated Y2H
32296183
种属内
SMIM1 B2RUZ4 KIR2DL3 Homo sapiens P43628
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 KIR2DL3 Homo sapiens P43628
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 CYB561 Homo sapiens P49447
Y2H Prey Pooling
32296183
种属内
SMIM1 B2RUZ4 CYB561 Homo sapiens P49447
Y2H Array
32296183
种属内
SMIM1 B2RUZ4 CYB561 Homo sapiens P49447
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Blood Group, Vel System

VEL
Tungiasis

Tunga Penetrans Infestation

Chigger Flea

S Penetrans

Sarcopsylla Penetrans

T Penetrans

Tunga Penetrans

Sand-Flea Infestation

Jiggers Infestation

Chigoe Infestation

Jigger Disease
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13436 SMIM1 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta SMIM1 VGNC VGNC:106497
Mus musculus SMIM1 MGD MGI:1916109
Canis familiaris SMIM1 VGNC VGNC:53448
Rattus norvegicus SMIM1 RGD RGD:1564257
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X

Y

Z

热 A B C F G H J L N Q S T X Y Z