2. Gene
  3. Tpo - thyroid peroxidase Gene

Tpo - thyroid peroxidase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 54314 | 基因类型: protein coding

关于 Tpo

功能概要

Predicted to enable iodide peroxidase activity. Involved in cellular response to nitric oxide and response to lipid. Located in cell surface and plasma membrane. Human ortholog(s) of this gene implicated in congenital hypothyroidism; glomerulonephritis; and thyroid dyshormonogenesis 2A. Orthologous to human TPO (thyroid peroxidase). [provided by Alliance of Genome Resources, Apr 2022]

Tpo 基因产物(1)

mRNA Protein Name
NM_019353.2 NP_062226.2 thyroid peroxidase precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to nitric oxide IEP
IEP: 通过表达模式推断
17714035 RGD
involved in response to lipid IEP
IEP: 通过表达模式推断
12748414 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
15917231 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

thyroid peroxidase

相关产品

Approval
生物活性分子 (5)
目录号 产品名 作用方式
纯度 是否罕见病
HY-19883 Lusutrombopag Agonist 98.88% 否
HY-13463 Avatrombopag Agonist 99.83% 是
HY-W017113 2-Mercaptobenzothiazole Activator 99.85% 是
HY-13463B Avatrombopag hydrochloride Agonist 97.05% 是
HY-13463A Avatrombopag maleate 99.88% 是
Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-145581 Mitiperstat Inhibitor 99.12% Phase 3
HY-145589 Rafutrombopag Agonist / Phase 1
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P990685 Romiplostim ≥99.0% Phase 4
Pre-clinical Phase
生物活性分子 (16)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-148748 Butyzamide Activator 99.62% 否
HY-112486 TA-316 99.50% 否
HY-W017894 TPO-L 99.40% 否
HY-112486G TA-316 (GMP) Agonist / 否
HY-100380 TPO agonist 1 Agonist ≥98.0% 否
HY-139915 MPO-IN-1 Inhibitor 98.07% 否
HY-15306S Eltrombopag-13C4 97.89% 否
HY-19883S Lusutrombopag-d13 Agonist 98.64% 否
HY-13463BS Avatrombopag-d8 hydrochloride Agonist / 否
HY-147691 MPO-IN-5 Inhibitor / 否
HY-153239 Eltrombopag methyl ester Agonist / 否
HY-RS14498 THPO Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS14941 TPO Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16596 Tpo Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17819 Thpo Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23030 Tpo Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tpo NCBI NCBI:7173
Macaca fascicularis Tpo NCBI NCBI:102125126
Mus musculus Tpo NCBI NCBI:22018
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