2. Gene
  3. POU5F1B - POU class 5 homeobox 1B Gene

POU5F1B - POU class 5 homeobox 1B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：POU 5 类同源框 1B

种属: Homo sapiens

同用名: OTF3C; OTF3P1; OCT4PG1; OCT4-PG1; POU5F1P1; POU5F1P4; POU5FLC8; POU5FLC20

基因 ID: 5462 | 基因类型: protein coding

关于 POU5F1B

Cytogenetic location: 8q24.21 Genomic coordinates (GRCh38): 8:127,413,447-127,417,224 (from NCBI)

This gene has 3 transcripts (splice variants), 316 orthologues and 17 paralogues.

功能概要

该无内含子基因被认为是 POU 类 5 同源框 1 的转录假基因，然而，据报道该基因可以编码功能蛋白。编码的蛋白质与 POU 5 类同源框 1 转录因子的长度几乎相同且高度相似，已被证明是一种弱转录激活因子，可能在致癌作用和眼睛发育中发挥作用。[RefSeq 提供，2009 年 4 月]

This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and highly similar to the POU class 5 homeobox 1 transcription factor, has been shown to be a weak transcriptional activator and may play a role in carcinogenesis and eye development. [provided by RefSeq, Apr 2009]

POU5F1B 基因产物(2)

mRNA Protein Name
NM_001159542.3 NP_001153014.1 putative POU domain, class 5, transcription factor 1B
NM_001395745.1 NP_001382674.1 putative POU domain, class 5, transcription factor 1B

POU5F1B 蛋白结构

Pou

Pou: Pou domain - N-terminal to homeobox domain (141 - 212)

Homeobox

Homeobox: Homeobox domain (231 - 286)

  • 0
  • 100
  • 200
  • 300
  • 359 a.a.
蛋白主名 其他名称

putative POU domain, class 5, transcription factor 1B

POU 5 domain protein

关联疾病

疾病名称 别名
Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10910 POU5F1B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus POU5F1B MGD MGI:101893
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z