1. Gene
  2. Rcan1 - regulator of calcineurin 1 Gene

Rcan1 - regulator of calcineurin 1 Gene

种属: Mus musculus

同用名: CSP1; DSC1; RCN1; Dscr1; MCIP1; CALP1L; Adapt78

基因 ID: 54720 | 基因类型: protein coding

关于 Rcan1

功能概要

Predicted to enable calcium-dependent protein serine/threonine Phosphatase regulator activity and identical protein binding activity. Acts upstream of or within several processes, including calcineurin-NFAT signaling cascade; response to ischemia; and short-term memory. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human RCAN1 (regulator of Calcineurin 1). [provided by Alliance of Genome Resources, Apr 2022]

Rcan1 基因产物(2)

mRNA Protein Name
NM_001081549.2 NP_001075018.1 calcipressin-1 isoform 1
NM_019466.4 NP_062339.2 calcipressin-1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12809556 MGI
enables protein phosphatase inhibitor activity IDA
IDA: 通过直接分析推断
16024798 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within calcineurin-NFAT signaling cascade IGI
IGI: 通过遗传相互作用推断
16648267 MGI
acts upstream of or within calcineurin-NFAT signaling cascade IMP
IMP: 通过突变表型推断
16648267 MGI
acts upstream of or within locomotion involved in locomotory behavior IGI
IGI: 通过遗传相互作用推断
16648267 MGI
acts upstream of or within response to ischemia IMP
IMP: 通过突变表型推断
16648267 MGI
acts upstream of or within response to oxidative stress IGI
IGI: 通过遗传相互作用推断
16648267 MGI
acts upstream of or within response to stress IGI
IGI: 通过遗传相互作用推断
16648267 MGI
acts upstream of or within response to stress IMP
IMP: 通过突变表型推断
16648267 MGI
acts upstream of or within short-term memory IGI
IGI: 通过遗传相互作用推断
16648267 MGI
acts upstream of or within skeletal muscle fiber development IDA
IDA: 通过直接分析推断
16024798 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
10722714 MGI
located in nucleus IDA
IDA: 通过直接分析推断
10722714 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

calcipressin-1

calcineurin inhibitor

down syndrome critical region protein 1 homolog

myocyte-enriched calcineurin-interacting protein 1

Rcan1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Rcan1 Q9JHG6 Fmr1 Mus musculus P35922 22863780
种属内
Rcan1 Q9JHG6 Dyrk1a Mus musculus Q61214 21965663
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rcan1 NCBI NCBI:1827