LYNX1 - Ly6/neurotoxin 1 Gene

中文名称：Ly6/神经毒素 1

种属: Homo sapiens

关于 LYNX1

功能概要

该基因编码 Ly6/uPAR (LU) 蛋白质超家族的 GPI 锚定细胞膜结合成员，其中包含独特的三指 LU 结构域。这种蛋白质与烟碱型乙酰胆碱受体 (nAChR) 相互作用，被认为可作为 nAChR 活性的调节剂发挥作用，以防止过度兴奋。已发现该基因的可变剪接转录物变体。该基因与相邻下游基因 (SLURP2) 之间的通读转录生成天然存在的转录本 (LYNX1-SLURP2) ，该转录本编码一种融合蛋白，该融合蛋白由与每个单独基因产物共享同一性的序列组成。[RefSeq 提供，2017 年 9 月]

This gene encodes a GPI-anchored, cell membrane bound member of the Ly6/uPAR (LU) superfamily of proteins containing the unique three-finger LU domain. This protein interacts with nicotinic acetylcholine receptors (nAChRs), and is thought to function as a modulator of nAChR activity to prevent excessive excitation. Alternatively spliced transcript variants have been found for this gene. Read-through transcription between this gene and the neighboring downstream gene (SLURP2) generates naturally-occurring transcripts (LYNX1-SLURP2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Sep 2017]