2. Gene
  3. Dnm1l - dynamin 1-like Gene

Dnm1l - dynamin 1-like Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Dlp1; Drp1; Dnmlp1; python; 6330417M19Rik

基因 ID: 74006 | 基因类型: protein coding

关于 Dnm1l

功能概要

This gene encodes a member of the Dynamin family. The encoded protein is localized to the cytoplasm and mitochondrial membrane, is involved in mitochondrial and peroxisomal division, and is essential for mitochondrial fission. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 2. [provided by RefSeq, Feb 2013]

Dnm1l 基因产物(22)

mRNA Protein Name
NM_001025947.3 NP_001021118.1 dynamin-1-like protein isoform b
NM_001276340.2 NP_001263269.1 dynamin-1-like protein isoform c
NM_001276341.2 NP_001263270.1 dynamin-1-like protein isoform d
NM_001360007.2 NP_001346936.1 dynamin-1-like protein isoform e
NM_001360008.2 NP_001346937.1 dynamin-1-like protein isoform f
NM_001360009.2 NP_001346938.1 dynamin-1-like protein isoform g
NM_001360010.2 NP_001346939.1 dynamin-1-like protein isoform h
NM_001405252.1 NP_001392181.1 dynamin-1-like protein isoform d
NM_001405253.1 NP_001392182.1 dynamin-1-like protein isoform i
NM_001405254.1 NP_001392183.1 dynamin-1-like protein isoform j
NM_001405255.1 NP_001392184.1 dynamin-1-like protein isoform k
NM_001405256.1 NP_001392185.1 dynamin-1-like protein isoform l
NM_001405257.1 NP_001392186.1 dynamin-1-like protein isoform m
NM_001405258.1 NP_001392187.1 dynamin-1-like protein isoform n
NM_001405259.1 NP_001392188.1 dynamin-1-like protein isoform o
NM_001405260.1 NP_001392189.1 dynamin-1-like protein isoform p
NM_001405261.1 NP_001392190.1 dynamin-1-like protein isoform q
NM_001405262.1 NP_001392191.1 dynamin-1-like protein isoform r
NM_001405263.1 NP_001392192.1 dynamin-1-like protein isoform s
NM_001405264.1 NP_001392193.1 dynamin-1-like protein isoform t
NM_001405265.1 NP_001392194.1 dynamin-1-like protein isoform t
NM_152816.4 NP_690029.2 dynamin-1-like protein isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22639965 MGI
enables protein homodimerization activity IPI
IPI: 通过物理相互作用推断
20585624 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within calcium ion transport IMP
IMP: 通过突变表型推断
28063983 MGI
involved in heart contraction IMP
IMP: 通过突变表型推断
20585624 MGI
acts upstream of or within mitochondrial fission IMP
IMP: 通过突变表型推断
20038678 MGI
involved in mitochondrial fission IMP
IMP: 通过突变表型推断
22265414 MGI
acts upstream of or within mitochondrion organization IMP
IMP: 通过突变表型推断
28063983 MGI
acts upstream of or within mitocytosis IMP
IMP: 通过突变表型推断
34048705 MGI
involved in peroxisome fission IMP
IMP: 通过突变表型推断
29853636 MGI
acts upstream of or within protein localization to mitochondrion IMP
IMP: 通过突变表型推断
24515348 MGI
involved in regulation of ATP metabolic process IMP
IMP: 通过突变表型推断
20585624 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
28063983 MGI
involved in regulation of mitochondrion organization IMP
IMP: 通过突变表型推断
20585624 MGI
involved in regulation of peroxisome organization IMP
IMP: 通过突变表型推断
20585624 MGI
acts upstream of or within regulation of ubiquitin protein ligase activity IMP
IMP: 通过突变表型推断
28063983 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in brush border IDA
IDA: 通过直接分析推断
22114352 MGI
located in cytosol IDA
IDA: 通过直接分析推断
30059978 MGI
located in cytosol IMP
IMP: 通过突变表型推断
23283981 MGI
located in mitochondrial outer membrane IDA
IDA: 通过直接分析推断
21149567 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
24515348 MGI
located in mitochondrion IMP
IMP: 通过突变表型推断
23283981 MGI
located in peroxisome IDA
IDA: 通过直接分析推断
29853636 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

dynamin-1-like protein

dymple

dynamin family member proline-rich carboxyl-terminal domain less

dynamin-related protein 1

Dnm1l 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Dnm1l Q8K1M6 Mief1 Mus musculus Q8BGV8
Crosslink
30914652
种属内
Dnm1l Q8K1M6 Mff Mus musculus Q6PCP5
Crosslink
30914652
种属内
Dnm1l Q8K1M6 Lrrk2 Mus musculus Q5S006
Anti Bait CoIP
22639965
种属内
Dnm1l Q8K1M6 Atad3 Mus musculus Q925I1
Anti Bait CoIP
30914652
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-N0484 Liensinine 99.97% Phase 2
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03904 DNM1L Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17698 Dnm1l Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24160 Dnm1l Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dnm1l NCBI NCBI:10059
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