1. Gene
  2. Stx4 - syntaxin 4 Gene

Stx4 - syntaxin 4 Gene

种属: Rattus norvegicus

同用名: Stx4a

基因 ID: 81803 | 基因类型: protein coding

关于 Stx4

功能概要

Enables several functions, including SNAP receptor activity; small GTPase binding activity; and spectrin binding activity. Involved in several processes, including exocytosis; membrane fusion; and protein localization to cell surface. Located in several cellular components, including basolateral plasma membrane; neuron projection membrane; and sarcolemma. Part of SNARE complex. Is active in glutamatergic synapse. Orthologous to human STX4 (syntaxin 4). [provided by Alliance of Genome Resources, Apr 2022]

Stx4 基因产物(1)

mRNA Protein Name
NM_031125.2 NP_112387.2 syntaxin-4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SNAP receptor activity IDA
IDA: 通过直接分析推断
19109692 RGD
enables SNARE binding IPI
IPI: 通过物理相互作用推断
10051443 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
10397765 RGD
enables small GTPase binding IPI
IPI: 通过物理相互作用推断
11063739 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in exocytic insertion of neurotransmitter receptor to postsynaptic membrane IDA
IDA: 通过直接分析推断
20434989 RGD
involved in exocytic insertion of neurotransmitter receptor to postsynaptic membrane IMP
IMP: 通过突变表型推断
20434989 RGD
involved in membrane fusion IDA
IDA: 通过直接分析推断
19109692 RGD
involved in protein localization to cell surface IMP
IMP: 通过突变表型推断
32963038 RGD
involved in protein-containing complex assembly IDA
IDA: 通过直接分析推断
10051443 RGD
involved in synaptic vesicle docking IDA
IDA: 通过直接分析推断
7690687 RGD
involved in vesicle-mediated transport in synapse IDA
IDA: 通过直接分析推断
20434989 RGD
involved in vesicle-mediated transport in synapse IMP
IMP: 通过突变表型推断
20434989 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of SNARE complex IDA
IDA: 通过直接分析推断
10051443 RGD
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
20434989 RGD
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
20434989 RGD
located in apical plasma membrane IDA
IDA: 通过直接分析推断
14759605 RGD
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
14759605 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
20434989 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
20434989 RGD
located in neuron projection membrane IDA
IDA: 通过直接分析推断
32963038 RGD
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
20434989 RGD
located in sarcolemma IDA
IDA: 通过直接分析推断
12388133 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

syntaxin-4

syntaxin 4A (placental)

Stx4 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Stx4 Q08850 Snap23 Mus musculus O09044 24469400
种属内
Stx4 Q08850 Vamp2 Rattus norvegicus P63045 23380067
种属内
Stx4 Q08850 Vamp2 Rattus norvegicus P63045 24469400
种属内
Stx4 Q08850 Vamp2 Rattus norvegicus P63045 24469400
种属间
Stx4 Q08850 Stxbp3 Mus musculus Q60770 24469400
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Stx4 NCBI NCBI:6810