1. Gene
  2. Xpo1 - exportin 1 Gene

Xpo1 - exportin 1 Gene

种属: Rattus norvegicus

同用名: exp1

基因 ID: 85252 | 基因类型: protein coding

关于 Xpo1

功能概要

Enables protein domain specific binding activity. Involved in negative regulation of transcription by RNA polymerase II; protein export from nucleus; and response to xenobiotic stimulus. Predicted to be located in several cellular components, including annulate lamellae; kinetochore; and nucleus. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human XPO1 (exportin 1). [provided by Alliance of Genome Resources, Apr 2022]

Xpo1 基因产物(1)

mRNA Protein Name
NM_053490.2 NP_445942.1 exportin-1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
27013579 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
10438867 RGD
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
11689633 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to salt IEP
IEP: 通过表达模式推断
27013579 RGD
involved in cellular response to triglyceride IEP
IEP: 通过表达模式推断
27013579 RGD
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
11689633 RGD
involved in protein export from nucleus IDA
IDA: 通过直接分析推断
11689633 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
11689633 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

exportin-1

chromosome region maintenance 1 protein homolog

exportin 1 (CRM1, yeast, homolog)

exportin 1, CRM1 homolog

Xpo1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Xpo1 Q80U96 NS2 Murine minute virus P0DJZ2 10438867
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Xpo1 NCBI NCBI:7514