1. Immunology/Inflammation
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  3. Mefenamic acid-d4

Mefenamic acid-d4  (Synonyms: 甲芬那酸 d4)

目录号: HY-B0574S 纯度: ≥98.0%
COA 产品使用指南

Mefenamic acid-d4 是 Mefenamic acid 的氘代物。Mefenamic acid 是一种非甾体抗炎剂,为竞争性的 hCOX-1hCOX-2 抑制剂,IC50 值分别为 40 nM 和 3 μM。

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Mefenamic acid-d<sub>4</sub> Chemical Structure

Mefenamic acid-d4 Chemical Structure

CAS No. : 1216745-79-7

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Other Forms of Mefenamic acid-d4:

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生物活性

Mefenamic acid-d4 is a deuterium labeled Mefenamic acid. Mefenamic acid is a non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1 and hCOX-2, with IC50s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively[1][2].

IC50 & Target

hCOX-1

40 nM (IC50)

hCOX-2

3 nM (IC50)

分子量

245.31

Formula

C15H11D4NO2

CAS 号
性状

固体

颜色

White to off-white

中文名称

甲芬那酸 d4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
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参考文献

Mefenamic acid-d4 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Mefenamic acid-d4
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